Neuronal Signaling Compound Library

Catalog No. L2600

Library Compound List Excel SDF

Communication between and within neurons is critical for all functions of the nervous system, from development to aging, through health and disease. The last decade has seen huge advances in our knowledge of the molecular, cellular and systematic signaling pathways within the nervous system. There have been significant breakthroughs in studies on the signaling pathways that underlie neurogenesis, addiction and autism spectrum disorders, as well as the pathophysiology and treatment of mood disorders. G protein-coupled receptors(GPCRs), including 5-HT receptors, histamine receptors, opioid receptors, are the largest family of signaling proteins to neuronal signaling. Changes in the GPCRs functioning can cause diseases many Neurological Disorders; Notch signaling is essential for proliferation, survival, self-renew, and differentiation of neural stem cells (NSCs). Notch signaling in neurons, glia and NSCs may be involved in pathological changes that occur in disorders such as stroke, Alzheimer’s disease and CNS tumors. Therefore, the potential of agents that target notch signaling could be used as therapeutic interventions for several different CNS disorders.

The Neuronal Signaling Compound Library by TargetMol, containing 2011 compounds targeting CNS signaling, can be used for high throughput screening and high content screening for new drugs in neurological disorders.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

Request for Quote

If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

Request Library

Product Description

A unique collection of 2011 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;
Bioactivity and safety confirmed by pre-clinical research and clinical trials;
Targets include 5-HT receptor, AChR, Histamine receptor, dopamine receptor, Opioid receptor, etc;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Library Composition

5-HT Receptor (288)

AChR (238)

COX (227)

Adrenergic Receptor (201)

Dopamine Receptor (186)

Histamine Receptor (134)

Autophagy (117)

GABA Receptor (110)

Apoptosis (100)

Endogenous Metabolite (94)

GluR (83)

AChE (77)

Opioid Receptor (72)

iGluR (67)

Adenosine Receptor (60)

NMDAR (58)

Beta Amyloid (50)

MAO (45)

Antibacterial (44)

NF-κB (38)

Monoamine Oxidase (37)

P-gp (37)

Prostaglandin Receptor (34)

Serotonin Transporter (34)

Potassium Channel (33)

Calcium Channel (32)

CaMK (30)

Parasite (30)

Gamma-secretase (30)

Norepinephrine (29)

P450 (28)

Neurokinin receptor (26)

P2X Receptor (23)

Cannabinoid Receptor (23)

Sodium Channel (21)

FAAH (20)

Hedgehog/Smoothened (20)

NO Synthase (19)

LPL Receptor (19)

S1P Receptor (19)

Sigma receptor (17)

Antibiotic (17)

PDE (17)

Reactive Oxygen Species (16)

OX Receptor (16)

TNF (16)

Influenza Virus (16)

Lipoxygenase (16)

HIV Protease (15)

Mitophagy (14)

P2Y Receptor (14)

Protease-activated Receptor (14)

Antifungal (14)

BACE (13)

Melanocortin Receptor (13)

Neuropeptide Y Receptor (12)

Ferroptosis (12)

Smo (11)

Beta-Secretase (11)

GPR (11)

PPAR (11)

NOS (10)

Endothelin Receptor (9)

Drug Metabolite (9)

Virus Protease (9)

Transferase (8)

GPCR19 (8)

PKA (8)

LPA Receptor (8)

IL Receptor (8)

ERK (7)

HDAC (7)

Caspase (7)

DNA/RNA Synthesis (7)

TRP/TRPV Channel (7)

Antioxidant (7)

Chloride channel (7)

PGE Synthase (7)

Phospholipase (7)

PKC (7)

Ras (6)

GlyT (6)

Glutathione Peroxidase (6)

ROS (6)

Glucagon Receptor (6)

BCL (6)

MT Receptor (6)

cAMP (6)

Melatonin Receptor (6)

Guanylate cyclase (6)

Estrogen/progestogen Receptor (6)

Interleukin (6)

MRP (5)

PI3K (5)

Microtubule Associated (5)

HSV (5)

SARS-CoV (5)

MMP (5)

p38 MAPK (5)

Tyrosinase (5)

Vasopressin Receptor (5)

AMPK (5)

Anti-infection (5)

GHSR (5)

Akt (5)

cholecystokinin (4)

IκB/IKK (4)

STAT (4)

Glucocorticoid Receptor (4)

Adenylyl cyclase (4)

Topoisomerase (4)

Histone Demethylase (4)

GRK (4)

HCV Protease (4)

VEGFR (4)

Monoamine Transporter (4)

FXR (3)

CaSR (3)

ROCK (3)

Casein Kinase (3)

Carbonic Anhydrase (3)

PAFR (3)

Mitochondrial Metabolism (3)

Phosphatase (3)

EGFR (3)

Androgen Receptor (3)

ABC (3)

Estrogen Receptor/ERR (3)

GNRH Receptor (3)

PARP (3)

NADPH (3)

Dehydrogenase (3)

Acyltransferase (3)

IAP (3)

Syk (3)

Imidazoline Receptor (3)

Histone Methyltransferase (3)

DYRK (2)

PAK (2)

GST (2)

advanced glycation end products (2)

NOD (2)

DNA (2)

CRFR (2)

Cysteine Protease (2)

GSK-3 (2)

RAAS (2)

CDK (2)

Src (2)

UGT (2)

TSH Receptor (2)

transporter (2)

TLR (2)

Thrombin (2)

TGF-beta/Smad (2)

ATPase (2)

CCR (2)

RSV (2)

Amino Acids and Derivatives (2)

BCRP (2)

Bombesin Receptor (2)

Bradykinin Receptor (2)

Progesterone Receptor (2)

EBI2/GPR183 (2)

Nrf2 (2)

Adiponectin receptor (2)

MAPK (2)

GTPase (2)

HBV (2)

HER (2)

Glucosidase (2)

HSP (2)

Hydroxylase (2)

IFNAR (2)

Immunology/Inflammation related (2)

JNK (2)

Leukotriene Receptor (2)

Lipase (2)

Gap Junction Protein (2)

Wnt/beta-catenin (2)

FAK (2)

Epigenetic Reader Domain (2)

mTOR (2)

c-RET (1)

HMG-CoA Reductase (1)

IGF-1R (1)

Serine/threonin kinase (1)

ATP Citrate Lyase (1)

Aryl Hydrocarbon Receptor (1)

Sirtuin (1)

Aminopeptidase (1)

Apelin receptor (1)

Somatostatin (1)

DNA Methyltransferase (1)

NOD-like Receptor (NLR) (1)

Stearoyl-CoA Desaturase (SCD) (1)

STING (1)

Myosin (1)

Na+/Ca2+ Exchanger (1)

Aurora Kinase (1)

Histone Acetyltransferase (1)

Antiviral (1)

Adenosine deaminase (1)

Transaminase (1)

HIF/HIF Prolyl-Hydroxylase (1)

NMU2R (1)

Trk receptor (1)

Antifolate (1)

GPX (1)

Antifection (1)

N-Acetylglucosaminyltransferase (1)

Annexin A (1)

NADPH-oxidase (1)

Anion Exchanger (1)

S6 Kinase (1)

GluCls (1)

p53 (1)

Platelet aggregation (1)

PAD (1)

FGFR (1)

FLAP (1)

FLT (1)

Melanin-concentrating Hormone Receptor (MCHR) (1)

MEK (1)

CFTR (1)

cell cycle arrest (1)

Oxytocin Receptor (1)

Free radical scavengers (1)

MAGL (1)

Pim (1)

CAT (1)

lysosomal autophagy (1)

Monocarboxylate transporter (1)

ROS Kinase (1)

ACK (1)

Epoxide Hydrolase (1)

LDL (1)

Fatty Acid Synthase (1)

JAK (1)

Raf (1)

Neurotensin Receptor (1)

Bcr-Abl (1)

Retinoid Receptor (1)

Reverse Transcriptase (1)

Rho (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

ROR (1)

CRISPR/Cas9 (1)

Integrin (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty