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Kinase Inhibitor Library

Catalog No. L1600

Library Compound List Excel SDF

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules (ATP) to specific substrates. This process is known as phosphorylation. The protein kinases make up the majority of all kinases and are widely studied. A protein kinase modifies other molecules, mostly proteins, by phosphorylation to regulate the majority of cellular pathways, especially those involved in signal transduction. Various other kinases act on small molecules such as lipids, carbohydrates, amino acids, and nucleotides, either for signaling or to prime them for metabolic pathways.

TargetMol’s Tyrosine Kinase Inhibitors Library, containing 1339 kinase inhibitors, can be used for research in chemical genomics, pharmacological study, and drug screening for related diseases.

Pack Size	Price/USD
100 μL * 10 mM (in DMSO)	18690.00
250 μL * 10 mM (in DMSO)	30610.00
1 mg	30610.00

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Product Description

A unique collection of 1339 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;
Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
Targets include MAPK, PI3K, JAK, STAT, CDK, MEK, Insulin/IGF receptors, CaM Kinease II, PKA, JNK, PKC, RAF, EGFR, SAPK, GSK, MLCK, Src-family, IKK, PDGFR, VEGFR, etc;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging and Storage

Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
Shipped with blue ice.

Supporting Files

Library Handling Instructions (927 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Library Composition

PI3K (73)

EGFR (62)

VEGFR (58)

CDK (56)

Src (42)

JAK (42)

PDGFR (42)

FLT (37)

mTOR (36)

c-Kit (35)

FGFR (33)

ALK (31)

PKC (29)

GSK-3 (26)

Bcr-Abl (25)

p38 MAPK (25)

c-Met/HGFR (24)

Akt (23)

ERK (23)

Raf (23)

Tyrosine Kinases (23)

DNA-PK (21)

Aurora Kinase (19)

MEK (18)

IκB/IKK (17)

PKA (15)

ATM/ATR (15)

ROCK (14)

IGF-1R (14)

TAM Receptor (13)

S6 Kinase (12)

JNK (12)

c-RET (12)

FAK (12)

HER (12)

Glucokinase (11)

Chk (11)

BTK (11)

CaMK (11)

Casein Kinase (10)

AMPK (10)

Serine/threonin kinase (10)

Syk (10)

PLK (10)

Trk receptor (10)

PDK (9)

LRRK2 (8)

Pim (8)

MAPK (8)

TGF-beta/Smad (8)

AChR (7)

DNA/RNA Synthesis (6)

TNF (6)

Kinesin (5)

PERK (5)

P450 (5)

NF-κB (5)

c-Fms (5)

cholecystokinin (5)

CSF-1R (5)

Dehydrogenase (4)

Adrenergic Receptor (4)

Autophagy (4)

STAT (4)

Serine Protease (4)

PDE (4)

PKM (4)

PYK2 (4)

Vitamin (4)

Topoisomerase (3)

PPAR (3)

Prostaglandin Receptor (3)

Rho (3)

ROS (3)

S1P Receptor (3)

SGK (3)

Na-K-Cl cotransporter (3)

Neurokinin 1 (3)

5-HT Receptor (3)

Adenosine Receptor (3)

Carbonic Anhydrase (3)

COX (3)

Dopamine Receptor (3)

Estrogen/progestogen Receptor (3)

HDAC (3)

GRK (3)

Histamine Receptor (3)

HSV (2)

Hck (2)

Glucocorticoid Receptor (2)

DYRK (2)

Ephrin Receptor (2)

Epigenetic Reader Domain (2)

DNA Alkylation (2)

ACK (2)

ASK (2)

Antiviral (2)

NADPH (2)

MPO (2)

KSP (2)

Lipoxygenase (2)

Microtubule Associated (2)

MLK (2)

MMP (2)

TOPK (2)

Sodium Channel (2)

Potassium Channel (2)

ROR (1)

PTEN (1)

Thrombin (1)

Tie-2 (1)

Sirtuin (1)

MNK (1)

Monoamine Transporter (1)

lysosomal autophagy (1)

Melatonin Receptor (1)

MELK (1)

IL Receptor (1)

Integrin (1)

LIM Kinase (1)

MTH1 (1)

NOD (1)

p53 (1)

PAK (1)

PARP (1)

Phosphatase (1)

Phospholipase (1)

Phosphorylase (1)

Apoptosis inducer (1)

Aromatase (1)

BCL (1)

ATP Citrate Lyase (1)

ATPase (1)

AhR (1)

Antifection (1)

Cysteine Protease (1)

c-Myc (1)

Calcium Channel (1)

cell cycle arrest (1)

E1/E2/E3 Enzyme (1)

GABA Receptor (1)

Factor Xa (1)

Fatty Acid Synthase (1)

HCV Protease (1)

Hedgehog/Smoothened (1)

GluR (1)

GST (1)

HIF (1)

Histone Demethylase (1)

HIV Protease (1)

HSP (1)

Wee1 (1)

Wnk (1)

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

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