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Compound Libraries Killers Collection

Killers Collection

Catalog No. L5500
  Library Compound List   Excel SDF

TargetMol’s Killer Collections include 277 synthetic and natural toxic substances that can alter cellular, metabolic and membrane functions, such as DNA/ RNA synthesis inhibitors, cytotoxic agents, immune suppressants, anti-proliferatives, endocrine disruptors and other agents. This special collection finds application in testing the sensitivity, development and profiling of new assays in high throughput screening (HTS) programs used in new drug discovery.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 3363.00
250 μL * 10 mM (in DMSO) 5917.00
1 mg 5917.00
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Product Description

  • A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS);
  • Covers more than 150 targets related to immune diseases, neurological diseases, respiratory disorders, endocrine diseases, and cardiovascular diseases.
  • Includes 222 drugs with certain studies on mechanisms of toxicity;
  • Includes 89 natural products, most of which are effective ingredients of Chinese medicine and attractive for toxicological study.
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

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Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice.
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Library Composition

DNA/RNA Synthesis (42)
AChR (16)
COX (12)
Dehydrogenase (12)
Topoisomerase (12)
DNA Alkylation (10)
Potassium Channel (10)
Histamine Receptor (9)
Dopamine Receptor (7)
Adrenergic Receptor (7)
PDE (7)
ribosome (6)
5-HT Receptor (6)
ATPase (5)
GABA Receptor (5)
NMDAR (4)
P450 (3)
mTOR (3)
PPAR (3)
GR (3)
HDAC (3)
MAO (3)
Microtubule Associated (3)
Antifection (3)
Aromatase (3)
Antibacterial (3)
Calcium Channel (3)
Phospholipase (3)
STAT (3)
Vitamin (3)
Opioid Receptor (2)
TNF (2)
VEGFR (2)
PKA (2)
Sodium Channel (2)
ROS (2)
Carbonic Anhydrase (2)
Casein Kinase (2)
CAT (2)
Chloride channel (2)
DNA Methyltransferase (2)
EGFR (2)
Antibiotic (2)
Akt (2)
Bcr-Abl (2)
HSV (2)
HCV Protease (2)
NF-κB (2)
MRP (2)
Norepinephrine (2)
Nucleoside Antimetabolite/Analog (1)
p53 (1)
MTH1 (1)
Proteasome (1)
Proton pump (1)
Raf (1)
Retinoid Receptor (1)
Reverse Transcriptase (1)
Rho (1)
GluR (1)
GPR (1)
Hedgehog/Smoothened (1)
HIV Protease (1)
IGF-1R (1)
Lipoxygenase (1)
lysosomal autophagy (1)
MMP (1)
MPO (1)
Autophagy (1)
BCL (1)
ATM/ATR (1)
Antifungal (1)
Amino Acids and Derivatives (1)
AhR (1)
Adenosine Receptor (1)
Estrogen/progestogen Receptor (1)
Factor Xa (1)
FGFR (1)
DUB (1)
Cell wall (1)
DNA gyrase (1)
DNA (1)
RSV (1)
Sigma receptor (1)
Sirtuin (1)
PI3K (1)
Phosphatase (1)
Src (1)
PKC (1)
Syk (1)
Thyroid hormone receptor(THR) (1)
TLR (1)
Wnt/beta-catenin (1)
Transferase (1)
Tyrosinase (1)
UGT (1)