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Compound Libraries Ion Channel Inhibitor Library

Ion Channel Inhibitor Library

Catalog No. L2300
  Library Compound List   Excel SDF

Given the central functional role that the ion channel superfamily plays in human physiology, its membrane localization, and the diverse tissue distribution of different members of the family, it represents an attractive potential target class for drug discovery. Ion channelsplay a fundamental role in the way cells communicate. This communication between cells allows for the orchestration of physical and mental activities in humans. A number of diseases occur when ion channels do not function properly. Some examples are diabetes, neuropathic pain, cardiovascular diseases, asthma, epilepsy, and neurodegenerative disease, etc.

The Ion Channel Inhibitor Library by TargetMol, containing 362 compounds targeting ion channels, can be used for research in ion channel, high throughput screening and high content screening for ion channel drug discovery.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 4056.00
250 μL * 10 mM (in DMSO) 7284.00
1 mg 7284.00
Top Publication Citing Use of Targetmol Products
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Product Description

  • A unique collection of 362 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Targets include potassium channel, calcium channel, sodium channel, Proton pump, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice.

Supporting Files

Library Handling Instructions (927 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L2300)

Library Composition

Potassium Channel (56)
Sodium Channel (55)
Calcium Channel (44)
GABA Receptor (35)
AChR (25)
ATPase (23)
TRP/TRPV Channel (15)
NMDAR (13)
5-HT Receptor (11)
Adrenergic Receptor (10)
GluR (10)
CFTR (10)
Proton pump (10)
Dopamine Receptor (9)
COX (9)
SGLT (7)
EGFR (6)
ABC (6)
MRP (6)
Histamine Receptor (5)
CaMK (5)
Carbonic Anhydrase (5)
Monocarboxylate transporter (4)
P2 Receptor (4)
P450 (4)
PPAR (4)
OCT (4)
P-gp (3)
NPC1L1 (3)
Integrin (3)
NADPH (3)
Na-K-Cl cotransporter (3)
NF-κB (3)
Chloride channel (3)
CRM1 (3)
GluCls (2)
AhR (2)
Autophagy (2)
Androgen Receptor (2)
LDL (2)
Lipid (2)
MMP (2)
Monoamine Transporter (2)
HER (2)
HIF (2)
OAT (2)
Norepinephrine (2)
Phosphatase (2)
Opioid Receptor (2)
TNF (2)
Topoisomerase (2)
Platelet aggregation (2)
VEGFR (2)
transporter (1)
UGT (1)
Sigma receptor (1)
Src (1)
Syk (1)
Prostaglandin Receptor (1)
RAAS (1)
ribosome (1)
ROR (1)
Serine Protease (1)
Phospholipase (1)
PKC (1)
PDE (1)
NOS (1)
NOD (1)
Nrf2 (1)
IκB/IKK (1)
HMG-CoA Reductase (1)
IAP (1)
IL Receptor (1)
Lipoxygenase (1)
mTOR (1)
Annexin A (1)
Antibacterial (1)
Antifection (1)
Apoptosis inducer (1)
ACAT (1)
Adenosine Receptor (1)
Adiponectin receptor (1)
BCL (1)
Bcr-Abl (1)
Beta Amyloid (1)
AMPK (1)
Glucocorticoid Receptor (1)
Gap Junction Protein (1)
GR (1)
HBV (1)
HDAC (1)
Dehydrogenase (1)
DNA gyrase (1)
DNA Methyltransferase (1)
Estrogen/progestogen Receptor (1)
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