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Ion Channel Inhibitor Library

Catalog No. L2300

Library Compound List Excel SDF

Given the central functional role that the ion channel superfamily plays in human physiology, its membrane localization, and the diverse tissue distribution of different members of the family, it represents an attractive potential target class for drug discovery. Ion channelsplay a fundamental role in the way cells communicate. This communication between cells allows for the orchestration of physical and mental activities in humans. A number of diseases occur when ion channels do not function properly. Some examples are diabetes, neuropathic pain, cardiovascular diseases, asthma, epilepsy, and neurodegenerative disease, etc.

The Ion Channel Inhibitor Library by TargetMol, containing 705 compounds targeting ion channels, can be used for research in ion channel, high throughput screening and high content screening for ion channel drug discovery.

Pack Size	Price/USD
100 μL * 10 mM (in DMSO)	6333.00
250 μL * 10 mM (in DMSO)	11175.00
1 mg	11175.00

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Product Description

A unique collection of 705 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
Targets include potassium channel, calcium channel, sodium channel, Proton pump, etc;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (927 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Library Composition

Potassium Channel (99)

Calcium Channel (84)

GABA Receptor (78)

Sodium Channel (78)

TRP/TRPV Channel (60)

AChR (43)

ATPase (38)

NMDAR (24)

Chloride channel (18)

COX (16)

GluR (15)

5-HT Receptor (15)

Adrenergic Receptor (15)

CFTR (13)

P-gp (12)

P450 (11)

SGLT (11)

Proton pump (11)

Dopamine Receptor (11)

ABC (10)

EGFR (8)

P2 Receptor (8)

Histamine Receptor (7)

Carbonic Anhydrase (7)

CaMK (6)

Monoamine Transporter (6)

Monocarboxylate transporter (6)

IL Receptor (5)

NF-κB (5)

Endogenous Metabolite (5)

TNF (5)

GPR (4)

HER (4)

AMPK (4)

NPC1L1 (4)

OCT (4)

iGluR (4)

MRP (4)

PPAR (4)

PKC (4)

PDE (3)

PKA (3)

Platelet aggregation (3)

MMP (3)

Opioid Receptor (3)

NADPH (3)

Na-K-Cl cotransporter (3)

Antibacterial (3)

HIV Protease (3)

HMG-CoA Reductase (3)

Integrin (3)

CRM1 (3)

VDAC (3)

transporter (3)

VEGFR (2)

Estrogen/progestogen Receptor (2)

GlyT (2)

HIF (2)

Glucocorticoid Receptor (2)

Hedgehog/Smoothened (2)

AhR (2)

Cannabinoid Receptor (2)

BCRP (2)

Autophagy (2)

BCL (2)

Antifection (2)

Apoptosis (2)

Norepinephrine (2)

NOS (2)

LDL (2)

Lipid (2)

Lipoxygenase (2)

mTOR (2)

Syk (2)

ROS (2)

OAT (2)

Phospholipase (2)

PKM (1)

Prostaglandin Receptor (1)

Protease-activated Receptor (1)

PDK (1)

Phosphatase (1)

p97 (1)

PAI-1 (1)

Parasite (1)

PARP (1)

S1P Receptor (1)

S6 Kinase (1)

Serine Protease (1)

Serine/threonin kinase (1)

RAAS (1)

Reductase (1)

ribosome (1)

ROCK (1)

TGF-beta/Smad (1)

Thrombin (1)

Src (1)

STAT (1)

Sigma receptor (1)

Myosin (1)

Na+/Ca2+ Exchanger (1)

N-Acetylglucosaminyltransferase (1)

MT Receptor (1)

MAO (1)

Microtubule Associated (1)

Mitochondrial Metabolism (1)

Influenza Virus (1)

NOD (1)

NKCC (1)

Nrf2 (1)

P2X Receptor (1)

p38 MAPK (1)

Apoptosis inducer (1)

Aquaporin (1)

Bcr-Abl (1)

Beta Amyloid (1)

Beta-Secretase (1)

Casein Kinase (1)

Caspase (1)

CGRP Receptor (1)

Akt (1)

Amino Acids and Derivatives (1)

ACAT (1)

AChE (1)

Antibiotic (1)

Adenosine Receptor (1)

Adiponectin receptor (1)

Androgen Receptor (1)

Anion Exchanger (1)

Annexin A (1)

GR (1)

GST (1)

HBV (1)

HCN Channel (1)

HDAC (1)

IP3 Receptor (1)

IκB/IKK (1)

JNK (1)

IAP (1)

Gap Junction Protein (1)

GluCls (1)

FAAH (1)

ERK (1)

Dehydrogenase (1)

DNA gyrase (1)

DNA Methyltransferase (1)

DNA/RNA Synthesis (1)

DPP-4 (1)

c-Myc (1)

Wnt/beta-catenin (1)

Topoisomerase (1)

Transaminase (1)

Tyrosinase (1)

UGT (1)

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

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