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Compound Libraries Inhibitor Library

Inhibitor Library

Catalog No. L2000
  Library Compound List   Excel SDF

Cell signalingis part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development,tissue repair, andimmunity, as well as normal tissuehomeostasis. Errors in signaling interactions and cellularinformation processingare responsible for diseases such as cancer,auto-immunity, and diabetes.By understanding cell signaling, diseases may be treated more effectively.

Inhibitor library is a unique collection of 4784 compounds, each of which has clear inhibitory targets. It is an effective tool for research in cell signaling pathways and related diseases, and high throughput screening and high content screening for new drugs.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 41346.00
250 μL * 10 mM (in DMSO) 68965.00
1 mg 68965.00
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Product Description

  • A unique collection of 4784 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Covers various major targets including MAPK, PI3K, JAK, HDAC, VEGFR, CDK, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L2000)

Library Composition

AChR (157)
COX (143)
5-HT Receptor (126)
PI3K (107)
CDK (102)
DNA/RNA Synthesis (97)
EGFR (91)
VEGFR (91)
Dopamine Receptor (89)
Adrenergic Receptor (88)
Dehydrogenase (78)
Histamine Receptor (74)
HDAC (73)
Sodium Channel (68)
PDE (67)
Epigenetic Reader Domain (65)
Calcium Channel (63)
JAK (63)
Src (62)
Potassium Channel (62)
PDGFR (57)
P450 (57)
NF-κB (56)
Histone Methyltransferase (55)
FGFR (55)
Estrogen/progestogen Receptor (54)
Bcr-Abl (54)
mTOR (54)
FLT (53)
HIV Protease (52)
Microtubule Associated (50)
Topoisomerase (50)
Raf (49)
Antibacterial (49)
TNF (47)
RAAS (46)
TRP/TRPV Channel (44)
GABA Receptor (44)
c-Kit (43)
PKC (42)
p38 MAPK (41)
Autophagy (41)
c-Met/HGFR (40)
Akt (39)
ALK (39)
GluR (38)
MAO (38)
ERK (37)
BCL (35)
GSK-3 (35)
STAT (35)
Wnt/beta-catenin (35)
Tyrosine Kinases (33)
PPAR (33)
HCV Protease (33)
ATPase (33)
Androgen Receptor (31)
Apoptosis (30)
Glucocorticoid Receptor (30)
DNA-PK (30)
PARP (30)
HSP (29)
MEK (29)
Antifection (29)
Aurora Kinase (29)
BTK (28)
Carbonic Anhydrase (28)
NMDAR (28)
Antibiotic (27)
Tyrosinase (27)
MMP (26)
IκB/IKK (26)
IL Receptor (26)
Phosphatase (25)
ROS (24)
TAM Receptor (23)
GR (23)
ATM/ATR (23)
CXCR (22)
Norepinephrine (22)
TGF-beta/Smad (22)
ribosome (22)
Vitamin (22)
HIF (21)
Cysteine Protease (21)
Glucokinase (21)
GPR (21)
Casein Kinase (21)
CCR (20)
Gamma-secretase (20)
Histone Demethylase (20)
Lipoxygenase (20)
Phospholipase (20)
P2 Receptor (20)
S6 Kinase (20)
Prostaglandin Receptor (20)
Proteasome (19)
ROCK (19)
Integrin (19)
JNK (19)
HER (19)
c-RET (19)
DUB (18)
Caspase (18)
PKA (18)
Serine Protease (18)
Trk receptor (18)
Hedgehog/Smoothened (17)
LRRK2 (17)
CaMK (17)
Beta Amyloid (17)
Antifungal (16)
Adenosine Receptor (16)
Influenza Virus (16)
Opioid Receptor (16)
NOS (16)
Sirtuin (16)
Reverse Transcriptase (16)
Ras (15)
Transferase (15)
Mdm2 (15)
p53 (15)
Antiviral (15)
Chloride channel (14)
FAK (14)
PLK (14)
NOD (14)
IGF-1R (14)
Serine/threonin kinase (14)
SGLT (13)
Syk (13)
MAPK (13)
IDO (13)
MRP (13)
NADPH (13)
FAAH (13)
DPP-4 (13)
DNA Alkylation (13)
DNA Methyltransferase (13)
E1/E2/E3 Enzyme (12)
Endogenous Metabolite (12)
DNA gyrase (12)
AMPK (12)
HMG-CoA Reductase (12)
TLR (12)
Reductase (12)
Pim (11)
Aromatase (11)
Antioxidant (11)
Amino Acids and Derivatives (11)
Chk (11)
CSF-1R (10)
Endothelin Receptor (10)
BACE (10)
c-Fms (10)
c-Myc (10)
OX Receptor (10)
LTR (10)
Lipase (10)
Retinoid Receptor (10)
Rho (10)
Proton pump (10)
Thyroid hormone receptor(THR) (9)
Thrombin (9)
Kinesin (9)
Hydroxylase (9)
HIF/HIF Prolyl-Hydroxylase (9)
P-gp (9)
DHFR (9)
Factor Xa (8)
Fatty Acid Synthase (8)
Cannabinoid Receptor (8)
AhR (8)
ABC (8)
PDK (8)
Neurokinin receptor (8)
HSV (8)
transporter (8)
Protease-activated Receptor (8)
Sigma receptor (7)
S1P Receptor (7)
Histone Acetyltransferase (7)
IAP (7)
HBV (7)
LPA Receptor (7)
Nrf2 (7)
Monocarboxylate transporter (7)
Parasite (7)
Acetyl-CoA Carboxylase (7)
Apoptosis inducer (7)
CFTR (7)
Ephrin Receptor (7)
Discoidin Domain Receptor (DDR) (6)
Ferroptosis (6)
PERK (6)
PAK (6)
NAMPT (6)
Lipid (6)
SARS-CoV (6)
Tie-2 (6)
UGT (6)
Vasopressin Receptor (6)
Telomerase (6)
SGK (5)
Platelet aggregation (5)
IRE1 (5)
LIM Kinase (5)
GRK (5)
Neuropeptide Y Receptor (5)
MPO (5)
MLK (5)
Mitochondrial Metabolism (5)
NADPH-oxidase (5)
p97 (5)
Phosphorylase (5)
Porcupine (5)
CETP (5)
CAT (5)
BMI-1 (5)
cAMP (5)
Aminopeptidase (5)
Acyltransferase (4)
advanced glycation end products (4)
GNRH Receptor (4)
cholecystokinin (4)
Dynamin (4)
DYRK (4)
DprE1 (4)
PKM (4)
PD-1/PD-L1 (4)
PAD (4)
MNK (4)
Neprilysin (4)
Monoamine Transporter (4)
NPC1L1 (4)
GST (4)
GTPase (4)
Hck (4)
Immunology & Inflammation related (4)
Melanocortin Receptor (4)
LDL (4)
PYK2 (4)
PTEN (3)
Serotonin Transporter (3)
Smo (3)
STING (3)
Wee1 (3)
Wnk (3)
VDAC (3)
Hippo pathway (3)
Nucleoside Antimetabolite/Analog (3)
NO Synthase (3)
Monoamine Oxidase (3)
Na-K-Cl cotransporter (3)
MTH1 (3)
PAI-1 (3)
PED (3)
CRM1 (3)
DNA (3)
Deubiquitinase (3)
Decarboxylase (3)
GPX (3)
GlyT (3)
Free radical scavengers (3)
AChE (3)
ACAT (3)
ACK (3)
Arginase (3)
Bradykinin Receptor (3)
ASK (3)
ATP Citrate Lyase (3)
cell cycle arrest (3)
Carboxypeptidase(CPG2) (3)
CaSR (2)
Complement System (2)
BCRP (2)
Antifolate (2)
FLAP (2)
GPCR19 (2)
GHSR (2)
Glutaminase (2)
Glutathione Peroxidase (2)
Glutathione reductase (2)
Dehydrogenase inhibitor (2)
CRFR (2)
EBI2/GPR183 (2)
Electron transport (2)
PAFR (2)
OXPHOS (2)
PGE Synthase (2)
PI4K (2)
Myosin (2)
OAT (2)
Hexokinase (2)
Haspin Kinase (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
KSP (2)
Interleukin Related (2)
Liver X Receptor (2)
lysosomal autophagy (2)
Xanthine Oxidase (2)
Survivin (2)
VDA (2)
TOPK (2)
SIK (2)
RSV (2)
ROR (2)
Reactive Oxygen Species (2)
PTP1B (1)
RIP kinase (1)
Salt-Inducible Kinase (1)
Transaminase (1)
Stearoyl-CoA Desaturase (SCD) (1)
stilbene oxidase (1)
TACC (1)
Thrombopoietin Receptor (1)
Thioredoxin (1)
YAP (1)
Virus Protease (1)
MALT (1)
Melatonin Receptor (1)
MELK (1)
MicroRNA (1)
Melanin-concentrating Hormone Receptor (MCHR) (1)
IP3 Receptor  (1)
IRAK (1)
Isocitrate Dehydrogenase (IDH) (1)
LHRH (1)
Integrase (1)
Histone Acetylation (1)
Hydrogenase (1)
hCE (1)
HCN Channel (1)
OCT (1)
NKCC (1)
Na+/Ca2+ Exchanger (1)
N-Acetylglucosaminyltransferase (1)
MyD88 (1)
Mitophagy (1)
P2X Receptor (1)
DNA Stain (1)
DNA Alkylator/Crosslinker (1)
CPT (1)
Glucagon Receptor (1)
Gap Junction Protein (1)
gp120/CD4 (1)
FXR (1)
FOXO1 (1)
FABP (1)
Estrogen Receptor/ERR (1)
Epoxide Hydrolase (1)
Anion Exchanger (1)
Annexin A (1)
Aryl Hydrocarbon Receptor (1)
Aquaporin (1)
APC (1)
Apelin receptor (1)
aconitase (1)
Adenylyl cyclase (1)
Bombesin Receptor (1)
CGRP Receptor (1)
Cell wall (1)