Compound Libraries Human Endogenous Metabolite Compound Library

Human Endogenous Metabolite Compound Library

Catalog No. L2500
  Library Compound List   Excel SDF

Changes in biological status (such as hypoxia, nutrients, drugs) usually cause the perturbations in the concentrations and fluxes of specific endogenous metabolites involved in a number of key disease-related or other specific cellular pathways. Extensive efforts in recent years have been focused on metabolic alterations in cancer, the products of intermediary metabolism has been a topic of considerable research interest. Cancer cells exhibit profound alterations in their metabolism. The quantitative measurement of the dynamic multiparametric metabolites, identification and quantification of intermediary metabolism can better help predict the tumor progress, understand the metabolic pathways and molecular mechanism of carcinogenesis. Current researches mainly focus on energy metabolism targeted compounds, such as nucleotides, amino acids, lipids, saccharide, etc. For example, alterations of cellular lipidomics (choline, phosphatidylcholine, cholesterol, etc.) reported in cancer provides a major opportunity to treat and prevent cancer; alterations of glucose metabolism (abnormal pyruvate, lactate, and isobutyric acid, etc.) in cancer cells, which also have become the hotspots in cancer research and therapeutics by targeting lipid metabolism and glucose metabolism.

TargetMol’s collection of 910 endogenous metabolism-related compounds, Human Endogenous Metabolism Compound Library, can be used for research in endogenous metabolism-related diseases and drug screening.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 13000.00
250 μL * 10 mM (in DMSO) 23500.00
1 mg 23500.00
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Product Description

  • A unique collection of 910 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening;
  • Effective tool for research in endogenous metabolism-related diseases, exploring the tumorigenesis, and drug discovery;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L2500)

Library Composition

Vitamin (20)
Estrogen/progestogen Receptor (12)
Endogenous Metabolite (10)
Glucocorticoid Receptor (5)
GR (5)
5-HT Receptor (5)
AChR (4)
Adrenergic Receptor (4)
Androgen Receptor (4)
Amino Acids and Derivatives (3)
GABA Receptor (3)
Potassium Channel (3)
Retinoid Receptor (2)
ROR (2)
Thyroid hormone receptor(THR) (2)
NF-κB (2)
Nucleoside Antimetabolite/Analog (2)
GPCR19 (2)
MRP (2)
FXR (2)
Arginase (2)
ATPase (2)
Autophagy (1)
Beta Amyloid (1)
CaMK (1)
Carbonic Anhydrase (1)
CFTR (1)
c-Met/HGFR (1)
Decarboxylase (1)
Dehydrogenase (1)
DHFR (1)
DNA/RNA Synthesis (1)
Dopamine Receptor (1)
EGFR (1)
AMPK (1)
Antifungal (1)
Antioxidant (1)
Fatty Acid Synthase (1)
GluR (1)
Glutathione reductase (1)
GST (1)
Hedgehog/Smoothened (1)
HIF/HIF Prolyl-Hydroxylase (1)
Histamine Receptor (1)
HIV Protease (1)
LDL (1)
Lipase (1)
Melatonin Receptor (1)
Mitochondrial Metabolism (1)
MMP (1)
Monocarboxylate transporter (1)
MPO (1)
Opioid Receptor (1)
NOS (1)
P450 (1)
PDE (1)
Phosphorylase (1)
PI3K (1)
PKC (1)
PLK (1)
TNF (1)
Transferase (1)
Trk receptor (1)
TRP/TRPV Channel (1)
ROS (1)
PPAR (1)
Wnt/beta-catenin (1)