Cart
Compound Libraries FDA Approved & Pharmacopeial Drug Library

FDA Approved & Pharmacopeial Drug Library

Catalog No. L1010
  Library Compound List   Excel SDF

Traditional de novo drug discovery and development involves an HTS campaign for de novo candidate hits and requires highly specialized screening facilities and compound libraries containing several million compounds. It is a time consuming and expensive process. As the regulation for drug safety and efficacy is increasingly getting complex, the cost of developing new drugs is keeping skyrocket. Drug repositioning, also known as old drugs for new uses, is an effective strategy to find new indications for existing drugs and has recently drawn attention and has led to several blockbuster drugs because of its high efficiency and low-cost. High-content screens, new biomarkers, noninvasive imaging techniques, and advanced in bioinformatics have created new opportunities for pursuing novel indications for approved compounds.

Approved drugs all have known and well-characterized bioactivities, safety and bioavailability – properties which could dramatically accelerate drug development and optimization. Hits from this set will provide a significant head start in any drug optimization program. In addition, a growing number of compounds have been identified from this library that can functionally replace reprogramming transcription factors, enhance efficiency of iPSC generation and accelerate the reprogramming process by single use or a combination of several molecules.

TargetMol’s FDA Approved & Pharmacopeial Drug Library collects 2978 compounds from approved institutions such as FDA, EMA, PMDA, NMPA, etc. or pharmacopoeia such as USP, BP, JP, etc., which can be used for drug repositioning and cell induction.

In addtion, we provide the peptides and other drug molecules with low solution stability in the form of dry powder (set as Part B) in order to ensure the best using effect of the compound library and increase the probability of successful screening as much as possible.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 14890.00
250 μL * 10 mM (in DMSO) 29613.00
1 mg 29613.00
Request Library
Get quote

Product Description

  • 2978 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS);
  • All compounds collected in this library are drugs approved by FDA, EMA, PMDA, NMPA, etc. or included in pharmacopoeia such as USP, BP, JP, etc.;
  • An effective tool for discovering new with old drugs and new drug target identification;
  • Covers various research areas, such as Cancer, Cardiovascular disease, Neuroscience, Immunology/Inflammation, respiratory system disease, etc.
  • More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L1010)

Library Composition

AChR (147)
Adrenergic Receptor (140)
5-HT Receptor (132)
Antibiotic (127)
Antibacterial (115)
COX (108)
Dopamine Receptor (87)
Histamine Receptor (76)
DNA/RNA Synthesis (71)
Sodium Channel (66)
Estrogen/progestogen Receptor (62)
Potassium Channel (57)
Calcium Channel (54)
Endogenous Metabolite (50)
Glucocorticoid Receptor (50)
Topoisomerase (47)
PDE (45)
Autophagy (45)
GR (39)
Vitamin (37)
GABA Receptor (36)
RAAS (34)
P450 (33)
Dehydrogenase (33)
HIV Protease (33)
Antifungal (30)
VEGFR (30)
ribosome (29)
NF-κB (28)
EGFR (28)
MAO (27)
PPAR (27)
Microtubule Associated (26)
Antifection (26)
c-Kit (24)
Norepinephrine (22)
PDGFR (22)
Androgen Receptor (21)
Antioxidant (21)
HCV Protease (21)
Carbonic Anhydrase (20)
ATPase (18)
HDAC (18)
Opioid Receptor (18)
Parasite (16)
Prostaglandin Receptor (16)
TNF (16)
Bcr-Abl (16)
GluR (15)
DNA Alkylation (15)
Thrombin (15)
PKC (15)
Reverse Transcriptase (15)
MRP (15)
Tyrosinase (14)
Tyrosine Kinases (13)
Src (13)
ROS (13)
IL Receptor (13)
NMDAR (13)
FGFR (13)
FLT (13)
Antiviral (13)
Amino Acids and Derivatives (12)
DHFR (12)
DPP-4 (12)
JAK (12)
MMP (12)
Lipoxygenase (11)
Proton pump (11)
Retinoid Receptor (11)
Raf (11)
TRP/TRPV Channel (11)
HMG-CoA Reductase (11)
CDK (11)
DNA gyrase (10)
Thyroid hormone receptor(THR) (10)
NADPH (10)
STAT (9)
Proteasome (9)
Phospholipase (9)
SGLT (9)
GNRH Receptor (9)
c-Met/HGFR (9)
c-RET (9)
CaMK (9)
Aromatase (9)
ALK (8)
AMPK (8)
ABC (8)
CAT (8)
HBV (8)
Factor Xa (8)
Serine Protease (8)
PI3K (8)
Transferase (8)
mTOR (8)
Influenza Virus (8)
PARP (8)
P2 Receptor (8)
p38 MAPK (7)
Integrin (7)
IκB/IKK (7)
MEK (7)
Reductase (7)
HIF (7)
Chloride channel (7)
Akt (7)
Annexin A (6)
CFTR (6)
HER (6)
HSV (6)
Hydroxylase (6)
TAM Receptor (6)
NOS (6)
Neurokinin receptor (5)
Phosphatase (5)
MPO (5)
Lipid (5)
TGF-beta/Smad (5)
Trk receptor (5)
TLR (5)
Vasopressin Receptor (5)
ROCK (5)
PKA (5)
GPR (5)
Hedgehog/Smoothened (5)
GSK-3 (5)
ERK (5)
Cysteine Protease (5)
Cannabinoid Receptor (5)
Adenosine Receptor (5)
BCL (4)
BTK (4)
Beta Amyloid (4)
Cell wall (4)
CaSR (4)
DNA Methyltransferase (4)
Fatty Acid Synthase (4)
FXR (4)
Glucagon Receptor (4)
HSP (4)
S1P Receptor (4)
Sigma receptor (4)
Sirtuin (4)
UGT (4)
Wnt/beta-catenin (4)
LTR (4)
Monoamine Transporter (4)
MT Receptor (3)
LDL (3)
P-gp (3)
p53 (3)
NOD (3)
Nucleoside Antimetabolite/Analog (3)
Na-K-Cl cotransporter (3)
Serotonin Transporter (3)
Syk (3)
PKM (3)
PLK (3)
Histone Methyltransferase (3)
Glucokinase (3)
GPCR19 (3)
GST (3)
Guanylate cyclase (3)
Free radical scavengers (3)
Endothelin Receptor (3)
CXCR (3)
Decarboxylase (3)
AhR (3)
Arginase (3)
Apoptosis (3)
Apoptosis inducer (2)
ATP Citrate Lyase (2)
Aminopeptidase (2)
ACAT (2)
AChE (2)
CETP (2)
c-Fms (2)
CGRP Receptor (2)
Chk (2)
CCR (2)
Caspase (2)
DNA (2)
Ephrin Receptor (2)
Epigenetic Reader Domain (2)
FAK (2)
Ferroptosis (2)
Gap Junction Protein (2)
GHSR (2)
Glutathione reductase (2)
GlyT (2)
GluCls (2)
Histone Demethylase (2)
Hexokinase (2)
HIF/HIF Prolyl-Hydroxylase (2)
IGF-1R (2)
Protease-activated Receptor (2)
Platelet aggregation (2)
Serine/threonin kinase (2)
SARS-CoV (2)
ROR (2)
Rho (2)
Somatostatin (2)
Telomerase (2)
Neprilysin (2)
Oxytocin Receptor (2)
PDK (2)
MAPK (2)
JNK (2)
Integrase (2)
Melatonin Receptor (2)
Monocarboxylate transporter (2)
Monoamine Oxidase (2)
Mitochondrial Metabolism (2)
Mitophagy (2)
Melanocortin Receptor (1)
MTH1 (1)
N-Acetylglucosaminyltransferase (1)
NADPH-oxidase (1)
Immunology & Inflammation related (1)
IP3 Receptor  (1)
IRAK (1)
Mdm2 (1)
lysosomal autophagy (1)
Lipase (1)
PED (1)
PGE Synthase (1)
P2X Receptor (1)
p97 (1)
PAFR (1)
NKCC (1)
NPC1L1 (1)
Nrf2 (1)
OAT (1)
NOD-like Receptor (NLR) (1)
OX Receptor (1)
Thrombopoietin Receptor (1)
Xanthine Oxidase (1)
VDA (1)
S6 Kinase (1)
Smo (1)
Progesterone Receptor (1)
Phosphorylase (1)
RAR/RXR (1)
Ras (1)
Reactive Oxygen Species (1)
iGluR (1)
IAP (1)
IDO (1)
Hydrogenase (1)
GRK (1)
Hck (1)
Estrogen Receptor/ERR (1)
DNA Alkylator/Crosslinker (1)
Electron transport (1)
DUB (1)
DYRK (1)
Casein Kinase (1)
cAMP (1)
Beta-Secretase (1)
Bradykinin Receptor (1)
Aurora Kinase (1)
BACE (1)
cholecystokinin (1)
CRM1 (1)
CSF-1R (1)
Adiponectin receptor (1)
ACK (1)
Acyltransferase (1)
advanced glycation end products (1)
ATM/ATR (1)
Anion Exchanger (1)
Antifolate (1)
Anti-infection (1)