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Compound Libraries Epigenetics Compound Library

Epigenetics Compound Library

Catalog No. L1200
  Library Compound List   Excel SDF

Epigenetics is the study of molecular processes that influence the flow of information between a constant DNA sequence and variable gene expression patterns. This includes investigation of nuclear organization, DNA methylation, histone modification and RNA transcription. Epigenetic processes can result in intergenerational (heritable) effects as well as clonal propagation of cell identity without any mutational change in DNA sequence. Epigenetics has the potential to be a key element in a paradigm change of our understanding of aging, development, cancer, heart disease, psychological disorders, and other diseases. For example, Epigenetic modifications have a considerable effect on cancer. Changes in the pattern of histone modifications in the promoter sequences as epigenetic regulation lead to changes in chromatin structure thus may be the cause of altered gene expression by activation of oncogenes.

The Epigenetics Compound Library by TargetMol, containing 903 compounds related to epigenetic regulation, can be used for research in epigenetics, high throughput screening and high content screening for new drugs in epigenetic modification.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 13440.00
250 μL * 10 mM (in DMSO) 22370.00
1 mg 22370.00
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Product Description

  • Quantity: well-chosen 903 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Targets include HDAC, SIRT, HAT, and HMT, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description, providing reference for your experimental design;
  • NMR and LCMS/HPLC validated to ensure high purity and quality.
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice.
Request Library Compound List (L1200)

Library Composition

HDAC (49)
JAK (46)
Epigenetic Reader Domain (41)
Histone Methyltransferase (38)
Aurora Kinase (25)
Sirtuin (20)
PARP (18)
HIF (16)
Tyrosine Kinases (16)
FLT (14)
Histone Demethylase (13)
PKC (12)
DNA/RNA Synthesis (11)
CDK (10)
Src (10)
AMPK (9)
DNA Methyltransferase (8)
Pim (8)
Wnt/beta-catenin (8)
Topoisomerase (7)
EGFR (7)
Bcr-Abl (7)
HIF/HIF Prolyl-Hydroxylase (6)
VEGFR (6)
PKA (5)
c-RET (5)
PDGFR (4)
Microtubule Associated (4)
Histamine Receptor (4)
FGFR (4)
IκB/IKK (4)
Syk (4)
PPAR (4)
ROCK (4)
STAT (3)
Trk receptor (3)
PDE (3)
COX (3)
Casein Kinase (3)
AChR (3)
Adenosine Receptor (2)
Chk (2)
c-Kit (2)
Dehydrogenase (2)
DNA Alkylation (2)
Estrogen/progestogen Receptor (2)
MEK (2)
PI3K (2)
MAO (2)
p38 MAPK (2)
p53 (2)
mTOR (2)
NADPH (2)
Fatty Acid Synthase (2)
Hedgehog/Smoothened (2)
HER (2)
Sodium Channel (2)
RAAS (2)
Serine/threonin kinase (2)
Potassium Channel (2)
Proteasome (1)
PTEN (1)
S1P Receptor (1)
S6 Kinase (1)
Serine Protease (1)
SGK (1)
Sigma receptor (1)
Raf (1)
Tyrosinase (1)
Transferase (1)
TAM Receptor (1)
Thioredoxin (1)
TNF (1)
Vitamin (1)
GABA Receptor (1)
GSK-3 (1)
IGF-1R (1)
Integrin (1)
JNK (1)
LDL (1)
Lipoxygenase (1)
LRRK2 (1)
lysosomal autophagy (1)
NF-κB (1)
Mdm2 (1)
MLK (1)
PERK (1)
Phosphatase (1)
Factor Xa (1)
ERK (1)
DNA-PK (1)
DUB (1)
DNA gyrase (1)
c-Met/HGFR (1)
c-Myc (1)
CPT (1)
cholecystokinin (1)
5-HT Receptor (1)
BTK (1)
Carbonic Anhydrase (1)
Carboxypeptidase(CPG2) (1)
Adrenergic Receptor (1)
Autophagy (1)
Androgen Receptor (1)
ATM/ATR (1)
ATP Citrate Lyase (1)
ATPase (1)
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