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Cytokine Inhibitor Library

Catalog No. L3600

Cytokinesare a broad and loose category of smallproteins(~5–20kDa) that are important incell signaling, modulate thebalancebetween humoral and cell-based immune responses, and are heavilyinvolved inautoimmuneand inflammatory diseases. Blocking cytokine signaling pathways by biologics has shown clinical effectiveness in these diseases.

Cytokines act throughreceptors and activate related signaling to modulate gene expression and cell functions. Cytokine receptors activate many signaling pathways: JAK-STAT, NF-kB, MAPK, PI3K, etc. A number of small molecular weight inhibitors targeting cytokine signaling have been identified as research progresses and some are approved to be marketed. Cytokines Inhibitors Library from TargetMol, containing 182 compounds targeting cytokine signaling, can be used for high throughput and high content screening for drug discovery.

Pack Size	Price
100 μL * 10 mM (in DMSO)	USD 4282.00
250 μL * 10 mM (in DMSO)	USD 6060.00
1 mg	USD 6060.00

Product Description

A unique collection of 182 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
Bioactivity and safety confirmed by pre-clinical research and clinical trials, and most of them are approved to be marketed;
Targets cover various cytokines including IL, CSF, IFN, TNF, TGF-beta family, growth factors, chemokine family, etc;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.

Packaging and Storage

Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
Shipped with blue ice; Stable for One year as powder, 6 months at - 20 ° C in DMSO or 12months at -80 ° C in DMSO

Library Composition

Most Related Compound Categories