Cytokinesare a broad and loose category of smallproteins(~5–20kDa) that are important incell signaling, modulate thebalancebetween humoral and cell-based immune responses, and are heavilyinvolved inautoimmuneand inflammatory diseases. Blocking cytokine signaling pathways by biologics has shown clinical effectiveness in these diseases.
Cytokines act throughreceptors and activate related signaling to modulate gene expression and cell functions. Cytokine receptors activate many signaling pathways: JAK-STAT, NF-kB, MAPK, PI3K, etc. A number of small molecular weight inhibitors targeting cytokine signaling have been identified as research progresses and some are approved to be marketed. Cytokines Inhibitors Library from TargetMol, containing 182 compounds targeting cytokine signaling, can be used for high throughput and high content screening for drug discovery.
|100 μL * 10 mM (in DMSO)||USD 4282.00|
|250 μL * 10 mM (in DMSO)||USD 6060.00|
|1 mg||USD 6060.00|
The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.