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Compound Libraries Autophagy Compound Library

Autophagy Compound Library

Catalog No. L3200
  Library Compound List   Excel SDF

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 623 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 5584.00
250 μL * 10 mM (in DMSO) 9876.00
1 mg 9876.00
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Product Description

  • A unique collection of 623 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice.
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Library Composition

PI3K (39)
Autophagy (33)
HDAC (30)
Bcr-Abl (23)
mTOR (22)
VEGFR (19)
Calcium Channel (17)
c-Kit (16)
DNA/RNA Synthesis (15)
EGFR (15)
AChR (15)
NF-κB (15)
FLT (15)
Adrenergic Receptor (14)
Aurora Kinase (14)
COX (14)
Src (14)
DNA-PK (13)
PDGFR (13)
JAK (11)
Estrogen/progestogen Receptor (11)
TNF (11)
Potassium Channel (11)
Topoisomerase (10)
CXCR (10)
c-RET (9)
5-HT Receptor (9)
PKC (9)
Microtubule Associated (9)
P450 (8)
p53 (8)
PDE (8)
FGFR (8)
LRRK2 (8)
HIF (8)
ATM/ATR (8)
CDK (8)
DUB (8)
Sodium Channel (8)
Proteasome (8)
PPAR (7)
Raf (7)
Serine/threonin kinase (6)
Sirtuin (6)
Epigenetic Reader Domain (6)
c-Met/HGFR (6)
ATPase (6)
BCL (6)
Akt (6)
Histamine Receptor (6)
GR (6)
PKA (6)
p38 MAPK (5)
HMG-CoA Reductase (5)
MAO (5)
Mdm2 (5)
MEK (5)
IL Receptor (5)
ALK (5)
Dopamine Receptor (5)
ERK (4)
DNA Methyltransferase (4)
Amino Acids and Derivatives (4)
Apoptosis inducer (4)
Androgen Receptor (4)
Casein Kinase (4)
Caspase (4)
IκB/IKK (4)
Phospholipase (4)
Pim (4)
MRP (4)
MMP (4)
NADPH (4)
Trk receptor (4)
Tyrosine Kinases (4)
S6 Kinase (4)
ribosome (4)
ROCK (3)
RAAS (3)
ROS (3)
Serine Protease (3)
Retinoid Receptor (3)
STAT (3)
TLR (3)
Vitamin (3)
PARP (3)
lysosomal autophagy (3)
IGF-1R (3)
HSP (3)
Histone Methyltransferase (3)
Hedgehog/Smoothened (3)
HER (3)
GSK-3 (3)
Adenosine Receptor (3)
ABC (3)
Carbonic Anhydrase (3)
DNA Alkylation (3)
Cysteine Protease (3)
Dehydrogenase (3)
DHFR (3)
DPP-4 (3)
GABA Receptor (3)
Gamma-secretase (2)
Fatty Acid Synthase (2)
Cell wall (2)
Annexin A (2)
Beta Amyloid (2)
BTK (2)
CaMK (2)
Cannabinoid Receptor (2)
HBV (2)
HIV Protease (2)
HSV (2)
LDL (2)
LTR (2)
Phosphatase (2)
Norepinephrine (2)
NOS (2)
Opioid Receptor (2)
p97 (2)
transporter (2)
Thrombin (2)
TAM Receptor (2)
TRP/TRPV Channel (2)
Ras (2)
Reductase (2)
Prostaglandin Receptor (2)
Proton pump (1)
PTEN (1)
Reverse Transcriptase (1)
SGK (1)
Sigma receptor (1)
ROR (1)
Tyrosinase (1)
Transferase (1)
UGT (1)
Vasopressin Receptor (1)
VDA (1)
TGF-beta/Smad (1)
Survivin (1)
PAFR (1)
PAI-1 (1)
NMDAR (1)
NOD (1)
NPC1L1 (1)
Nrf2 (1)
Nucleoside Antimetabolite/Analog (1)
MPO (1)
PLK (1)
P2 Receptor (1)
PDK (1)
PERK (1)
P-gp (1)
Melatonin Receptor (1)
MAPK (1)
Lipid (1)
Lipoxygenase (1)
Integrin (1)
IAP (1)
IDO (1)
HIF/HIF Prolyl-Hydroxylase (1)
Hck (1)
GRK (1)
FOXO1 (1)
FXR (1)
CAT (1)
CCR (1)
BMI-1 (1)
BACE (1)
Antibacterial (1)
Antibiotic (1)
Antifection (1)
Antiviral (1)
Arginase (1)
Aromatase (1)
AhR (1)
ACK (1)
Aminopeptidase (1)
AMPK (1)
CFTR (1)
Chk (1)
CSF-1R (1)
DNA (1)
DNA gyrase (1)
Ferroptosis (1)
FAAH (1)
FAK (1)
GluCls (1)
Glucocorticoid Receptor (1)
GluR (1)
E1/E2/E3 Enzyme (1)