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Compound Libraries Anti-Fibrosis Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810
  Library Compound List   Excel SDF

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn’s disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol’s Anti-Fibrosis Compound Library collects 981 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 14598.00
250 μL * 10 mM (in DMSO) 24291.00
1 mg 24291.00
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Product features

  • A unique collection of 981 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L9810)

Library Composition

VEGFR (97)
COX (87)
Antioxidant (82)
PDGFR (55)
FGFR (53)
Wnt/beta-catenin (41)
NF-κB (38)
c-Kit (31)
Glucocorticoid Receptor (28)
TNF (27)
TGF-beta/Smad (27)
GR (26)
FLT (23)
EGFR (22)
Cannabinoid Receptor (19)
JAK (19)
Src (19)
PPAR (19)
STAT (18)
IL Receptor (18)
NADPH (17)
P450 (16)
Bcr-Abl (15)
MMP (13)
Autophagy (12)
Apoptosis (12)
Antibacterial (12)
c-RET (12)
ERK (12)
c-Met/HGFR (11)
p38 MAPK (11)
NOS (10)
Endogenous Metabolite (9)
Akt (9)
PDE (9)
Prostaglandin Receptor (9)
Tyrosine Kinases (9)
PKC (8)
Antifection (8)
Aurora Kinase (8)
BCL (8)
Caspase (8)
Lipoxygenase (8)
CDK (7)
DNA/RNA Synthesis (7)
AChR (7)
Raf (7)
ROS (7)
Tyrosinase (7)
Phospholipase (6)
Adrenergic Receptor (6)
ATPase (6)
Antiviral (6)
GABA Receptor (6)
CFTR (6)
LPA Receptor (6)
IκB/IKK (6)
HIV Protease (6)
HER (5)
JNK (5)
NADPH-oxidase (5)
Chk (5)
CSF-1R (5)
Dehydrogenase (5)
AMPK (5)
PI3K (5)
Potassium Channel (5)
PKA (4)
PARP (4)
Reductase (4)
S6 Kinase (4)
TAM Receptor (4)
Trk receptor (4)
Antifungal (4)
Antibiotic (4)
ALK (4)
Cysteine Protease (4)
CCR (4)
Epigenetic Reader Domain (4)
HIF (4)
GSK-3 (4)
Glucokinase (3)
Histamine Receptor (3)
HSP (3)
LDL (3)
NOD (3)
Nrf2 (3)
MPO (3)
MRP (3)
mTOR (3)
MAPK (3)
MEK (3)
c-Fms (3)
Estrogen/progestogen Receptor (3)
Adenosine Receptor (3)
Annexin A (3)
Beta Amyloid (3)
Topoisomerase (3)
UGT (3)
Syk (3)
Tie-2 (3)
TLR (3)
Serine Protease (3)
Sirtuin (3)
Retinoid Receptor (3)
Proteasome (2)
RAAS (2)
Vitamin (2)
TRP/TRPV Channel (2)
BACE (2)
Aromatase (2)
5-HT Receptor (2)
DNA gyrase (2)
Ephrin Receptor (2)
Calcium Channel (2)
CXCR (2)
MLK (2)
Opioid Receptor (2)
PDK (2)
Immunology & Inflammation related (2)
Influenza Virus (2)
Integrin (2)
IGF-1R (2)
IAP (2)
Hck (2)
HDAC (2)
GPR (2)
Free radical scavengers (2)
Guanylate cyclase (1)
hCE (1)
Hedgehog/Smoothened (1)
HMG-CoA Reductase (1)
Histone Methyltransferase (1)
IDO (1)
HSV (1)
Hydrogenase (1)
Hydroxylase (1)
Lipase (1)
Keap1-Nrf (1)
PGE Synthase (1)
Phosphatase (1)
p53 (1)
PAFR (1)
PAI-1 (1)
P2 Receptor (1)
Monoamine Oxidase (1)
Monocarboxylate transporter (1)
N-Acetylglucosaminyltransferase (1)
Melatonin Receptor (1)
Microtubule Associated (1)
Mitochondrial Metabolism (1)
LTR (1)
MAO (1)
Chloride channel (1)
c-Myc (1)
CaMK (1)
Casein Kinase (1)
cell cycle arrest (1)
CETP (1)
Discoidin Domain Receptor (DDR) (1)
DNA Alkylation (1)
FAAH (1)
FLAP (1)
Gamma-secretase (1)
Gap Junction Protein (1)
GHSR (1)
ABC (1)
Adiponectin receptor (1)
Amino Acids and Derivatives (1)
Aminopeptidase (1)
Androgen Receptor (1)
Anion Exchanger (1)
advanced glycation end products (1)
ASK (1)
ATM/ATR (1)
ATP Citrate Lyase (1)
Apoptosis inducer (1)
BVDV (1)
Transferase (1)
Wnk (1)
Telomerase (1)
Thrombin (1)
Sodium Channel (1)
Somatostatin (1)
Survivin (1)
Serine/threonin kinase (1)
SARS-CoV (1)
PTEN (1)
ribosome (1)
ROCK (1)
ROR (1)
PLK (1)