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Compound Libraries Anti-cancer Compound Library

Anti-cancer Compound Library

Catalog No. L2100
  Library Compound List   Excel SDF

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy, however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 4730 compounds with anti-tumor activity based on different characteristics and abnormal metabolism with cancer cells. All of these compounds are the small molecules modulating the metabolism, growth, invasion, and metastasis of tumor cells that can be used for tumor-related research and anti-tumor drug screening.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 37837.00
250 μL * 10 mM (in DMSO) 65578.00
1 mg 65578.00
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Product Description

  • A unique collection of 4730 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety profiled in (confirmed by) pre-clinical and clinical settings (research and trials);
  • Effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L2100)

Library Composition

AChR (130)
5-HT Receptor (120)
COX (120)
PI3K (115)
DNA/RNA Synthesis (113)
CDK (111)
Adrenergic Receptor (107)
EGFR (106)
VEGFR (103)
Autophagy (84)
Epigenetic Reader Domain (78)
NF-κB (77)
HDAC (74)
Estrogen/progestogen Receptor (73)
Apoptosis (70)
Histamine Receptor (69)
PPAR (68)
Dehydrogenase (67)
JAK (64)
Src (62)
TNF (60)
mTOR (60)
Potassium Channel (60)
Histone Methyltransferase (59)
Bcr-Abl (59)
Antibacterial (58)
Dopamine Receptor (58)
Topoisomerase (58)
PDGFR (57)
Microtubule Associated (56)
FGFR (55)
ERK (53)
FLT (51)
Raf (50)
PKC (48)
STAT (48)
p38 MAPK (47)
P450 (47)
Akt (47)
c-Kit (46)
Wnt/beta-catenin (46)
c-Met/HGFR (45)
PDE (45)
ALK (41)
GABA Receptor (41)
BCL (39)
HSP (38)
AMPK (37)
GSK-3 (35)
IL Receptor (35)
RAAS (34)
Antioxidant (34)
Tyrosine Kinases (34)
Sodium Channel (34)
Glucocorticoid Receptor (33)
PARP (33)
MEK (32)
Antibiotic (32)
Androgen Receptor (31)
Caspase (31)
Endogenous Metabolite (31)
DNA-PK (31)
Aurora Kinase (29)
MAO (28)
Sirtuin (28)
BTK (27)
Carbonic Anhydrase (26)
Antifection (26)
ATPase (26)
GR (26)
Integrin (26)
JNK (25)
HIF (25)
Parasite (25)
TRP/TRPV Channel (25)
TAM Receptor (24)
HER (24)
IκB/IKK (24)
ATM/ATR (24)
Apoptosis inducer (24)
Antiviral (23)
Amino Acids and Derivatives (23)
DNA Alkylation (23)
HIV Protease (23)
S6 Kinase (23)
PKA (23)
Proteasome (23)
TGF-beta/Smad (23)
Tyrosinase (22)
Trk receptor (22)
Histone Demethylase (22)
c-RET (22)
CXCR (22)
Calcium Channel (22)
Gamma-secretase (20)
Hedgehog/Smoothened (20)
ROS (20)
Retinoid Receptor (20)
p53 (19)
GPR (19)
Cysteine Protease (18)
Casein Kinase (18)
Ras (18)
MAPK (18)
Mdm2 (18)
MMP (18)
Vitamin (18)
TLR (17)
Serine Protease (17)
LRRK2 (17)
NOS (17)
ROCK (16)
IGF-1R (16)
FAK (16)
Syk (16)
CCR (15)
CaMK (15)
Adenosine Receptor (15)
Reverse Transcriptase (15)
Norepinephrine (15)
Phospholipase (14)
MRP (14)
Chk (14)
DUB (14)
DNA gyrase (13)
DNA Methyltransferase (13)
GluR (13)
Lipoxygenase (13)
PLK (13)
Transferase (13)
Serine/threonin kinase (13)
NADPH (12)
IDO (12)
Glucokinase (12)
CFTR (11)
Beta Amyloid (11)
Aromatase (11)
HIF/HIF Prolyl-Hydroxylase (11)
HMG-CoA Reductase (11)
Pim (11)
S1P Receptor (11)
Prostaglandin Receptor (10)
NMDAR (10)
Opioid Receptor (10)
PERK (10)
Antifungal (10)
c-Fms (10)
DHFR (10)
CSF-1R (10)
Thrombin (10)
E1/E2/E3 Enzyme (9)
Fatty Acid Synthase (9)
PDK (9)
Nucleoside Antimetabolite/Analog (9)
Phosphatase (9)
Rho (9)
HSV (9)
Histone Acetyltransferase (8)
Liver X Receptor (8)
ribosome (8)
Proton pump (8)
Nrf2 (8)
P-gp (8)
HCV Protease (8)
BACE (8)
AhR (8)
Cannabinoid Receptor (7)
c-Myc (7)
PAK (7)
PKM (7)
Hydroxylase (7)
Kinesin (7)
Telomerase (7)
transporter (7)
UGT (7)
Tie-2 (6)
IAP (6)
Monocarboxylate transporter (6)
ROR (6)
PD-1/PD-L1 (6)
NOD (6)
Chloride channel (6)
CAT (6)
ABC (6)
FXR (6)
Ephrin Receptor (6)
Discoidin Domain Receptor (DDR) (5)
DNA (5)
HBV (5)
Ferroptosis (5)
Factor Xa (5)
BMI-1 (5)
P2 Receptor (5)
p97 (5)
Platelet aggregation (5)
Protease-activated Receptor (5)
MPO (5)
Mitochondrial Metabolism (5)
NAMPT (5)
MLK (5)
Reductase (5)
SGLT (5)
STING (5)
Sigma receptor (4)
SGK (4)
MNK (4)
Lipase (4)
LTR (4)
Porcupine (4)
PYK2 (4)
PAI-1 (4)
OCT (4)
cholecystokinin (4)
ATP Citrate Lyase (4)
Arginase (4)
Annexin A (4)
Free radical scavengers (4)
Hck (4)
GRK (4)
Dynamin (4)
DYRK (4)
DPP-4 (4)
DprE1 (3)
Deubiquitinase (3)
CRM1 (3)
GNRH Receptor (3)
GPCR19 (3)
GST (3)
GTPase (3)
Antifolate (3)
ASK (3)
ACAT (3)
ACK (3)
Aminopeptidase (3)
CETP (3)
cell cycle arrest (3)
cAMP (3)
OX Receptor (3)
OXPHOS (3)
Na-K-Cl cotransporter (3)
PAD (3)
PAFR (3)
PTEN (3)
lysosomal autophagy (3)
Lipid (3)
LPA Receptor (3)
LIM Kinase (3)
LDL (3)
Mitophagy (3)
MTH1 (3)
IRE1 (3)
Influenza Virus (3)
Survivin (3)
Thyroid hormone receptor(THR) (3)
Vasopressin Receptor (3)
VDA (2)
Wee1 (2)
Wnk (2)
TOPK (2)
SIK (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
IRAK (2)
KSP (2)
Hippo pathway (2)
Hexokinase (2)
Phosphorylase (2)
PI4K (2)
RIP kinase (2)
Reactive Oxygen Species (2)
PED (2)
NPC1L1 (2)
Carboxypeptidase(CPG2) (2)
BCRP (2)
CaSR (2)
AChE (2)
Acyltransferase (2)
GPX (2)
Haspin Kinase (2)
Glutaminase (2)
Glutathione reductase (2)
GlyT (2)
Gap Junction Protein (2)
GHSR (2)
Decarboxylase (2)
DNA Alkylator/Crosslinker (2)
FAAH (2)
Fas/FasL (1)
Estrogen Receptor/ERR (1)
Endothelin Receptor (1)
Electron transport (1)
DNA Stain (1)
Dehydrogenase inhibitor (1)
Glucagon Receptor (1)
GluCls (1)
FOXO1 (1)
Glutathione Peroxidase (1)
hCE (1)
Guanylate cyclase (1)
Adiponectin receptor (1)
Acetyl-CoA Carboxylase (1)
advanced glycation end products (1)
Cell wall (1)
CPT (1)
Beta-Secretase (1)
BVDV (1)
NOD-like Receptor (NLR) (1)
NKCC (1)
P2X Receptor (1)
OAT (1)
PGE Synthase (1)
Salt-Inducible Kinase (1)
SARS-CoV (1)
RAR/RXR (1)
Histone Acetylation (1)
Hydrogenase (1)
Keap1-Nrf (1)
Isocitrate Dehydrogenase (IDH) (1)
Integrase (1)
Interleukin Related (1)
Immunology & Inflammation related (1)
MT Receptor (1)
Neurokinin receptor (1)
NADPH-oxidase (1)
Monoamine Transporter (1)
LHRH (1)
MALT (1)
Melatonin Receptor (1)
MELK (1)
MicroRNA (1)
Smo (1)
Serotonin Transporter (1)
Somatostatin (1)
Stearoyl-CoA Desaturase (SCD) (1)
Stemness kinase (1)
Thioredoxin (1)
TACC (1)
Virus Protease (1)
Xanthine Oxidase (1)