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Compound Libraries Anti-Metabolism Disease Compound Library

Anti-Metabolism Disease Compound Library

Catalog No. L5200
  Library Compound List   Excel SDF

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of the cells and the organism, including catabolism and anabolism, and is one way the body maintains homeostasis. The main focus in metabolism research area is the biological regulatory mechanism and its role in obesity, diabetes, cardiovascular diseases, and cancer. The unique collection of 1040 small chemicals targeting metabolism diseases will provide the support for metabolism research and related drug screening.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 12480.00
250 μL * 10 mM (in DMSO) 20800.00
1 mg 20800.00
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Product Description

  • A unique collection of 1040 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or CFDA;
  • Covers various major targets including CYP, FAAH, IDO, MAO, etc., in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc.; Effective tool for cell metabolism research;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

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Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice.
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Library Composition

Dehydrogenase (50)
PDE (40)
GR (38)
P450 (37)
PPAR (37)
Vitamin (30)
COX (28)
MAO (26)
Potassium Channel (21)
Carbonic Anhydrase (19)
AChR (18)
HSP (17)
Phospholipase (17)
RAAS (16)
HIV Protease (13)
DNA/RNA Synthesis (13)
NADPH (12)
Retinoid Receptor (12)
Transferase (12)
Glucokinase (11)
HIF (10)
DHFR (10)
Casein Kinase (10)
Proteasome (10)
Thrombin (9)
HMG-CoA Reductase (9)
GPR (9)
NF-κB (9)
Lipoxygenase (8)
Lipase (8)
DPP-4 (8)
Serine Protease (8)
ROS (7)
transporter (7)
Estrogen/progestogen Receptor (7)
Factor Xa (7)
Cysteine Protease (7)
AhR (7)
Autophagy (7)
Lipid (7)
FXR (7)
MRP (7)
HCV Protease (6)
IDO (6)
Histamine Receptor (6)
Adrenergic Receptor (6)
5-HT Receptor (6)
FAAH (6)
Wnt/beta-catenin (6)
Reductase (6)
SGLT (6)
PKA (5)
Tyrosinase (5)
Sodium Channel (5)
Fatty Acid Synthase (5)
CAT (5)
Calcium Channel (5)
Annexin A (5)
HIF/HIF Prolyl-Hydroxylase (5)
IL Receptor (5)
GluR (5)
MMP (5)
MPO (5)
Liver X Receptor (5)
LDL (4)
Microtubule Associated (4)
NOS (4)
HDAC (4)
Hydroxylase (4)
AMPK (4)
Cannabinoid Receptor (4)
Antifection (4)
CDK (4)
CETP (4)
TNF (4)
UGT (4)
VEGFR (4)
PKC (4)
PKM (4)
Reverse Transcriptase (4)
ribosome (4)
SGK (3)
Proton pump (3)
PI3K (3)
ROR (3)
cholecystokinin (3)
Caspase (3)
Dopamine Receptor (3)
DNA Alkylation (3)
ABC (3)
Akt (3)
Bcr-Abl (3)
Antibacterial (3)
ATPase (3)
Integrin (3)
IκB/IKK (3)
HBV (3)
GSK-3 (3)
Glutathione reductase (3)
LTR (3)
mTOR (2)
NADPH-oxidase (2)
NMDAR (2)
P2 Receptor (2)
OAT (2)
Opioid Receptor (2)
p53 (2)
PDK (2)
PED (2)
PERK (2)
GABA Receptor (2)
Glucagon Receptor (2)
Glucocorticoid Receptor (2)
Amino Acids and Derivatives (2)
Aminopeptidase (2)
Adenosine Receptor (2)
ACAT (2)
Acetyl-CoA Carboxylase (2)
ERK (2)
Ferroptosis (2)
FLT (2)
Chloride channel (2)
c-RET (2)
TRP/TRPV Channel (2)
Topoisomerase (2)
Somatostatin (2)
TAM Receptor (2)
NAMPT (2)
Phosphatase (2)
Sirtuin (2)
S6 Kinase (1)
ROCK (1)
Raf (1)
RAR/RXR (1)
Ras (1)
PDGFR (1)
Pim (1)
Phosphorylase (1)
PTEN (1)
Prostaglandin Receptor (1)
Platelet aggregation (1)
Telomerase (1)
TGF-beta/Smad (1)
Thioredoxin (1)
Src (1)
Syk (1)
Thyroid hormone receptor(THR) (1)
Trk receptor (1)
Vasopressin Receptor (1)
VDA (1)
Tyrosine Kinases (1)
Decarboxylase (1)
c-Met/HGFR (1)
c-Myc (1)
Carboxypeptidase(CPG2) (1)
cell cycle arrest (1)
CCR (1)
Free radical scavengers (1)
DNA gyrase (1)
Dehydrogenase inhibitor (1)
EGFR (1)
Epigenetic Reader Domain (1)
DNA-PK (1)
ALK (1)
Antioxidant (1)
Antiviral (1)
Arginase (1)
Aromatase (1)
ASK (1)
ATM/ATR (1)
ATP Citrate Lyase (1)
Androgen Receptor (1)
Aurora Kinase (1)
BMI-1 (1)
Bombesin Receptor (1)
BACE (1)
CaMK (1)
Gap Junction Protein (1)
GPCR19 (1)
GSNOR (1)
GST (1)
Hedgehog/Smoothened (1)
JAK (1)
IAP (1)
Histone Demethylase (1)
Histone Methyltransferase (1)
HSV (1)
Hydrogenase (1)
P-gp (1)
PAI-1 (1)
PARP (1)
p38 MAPK (1)
NPC1L1 (1)
Nrf2 (1)
Na-K-Cl cotransporter (1)
Monocarboxylate transporter (1)
LPA Receptor (1)
Mdm2 (1)
MEK (1)
Melatonin Receptor (1)