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Compound Libraries Anti-Metabolism Disease Compound Library

Anti-Metabolism Disease Compound Library

Catalog No. L5200
  Library Compound List   Excel SDF

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of the cells and the organism, including catabolism and anabolism, and is one way the body maintains homeostasis. The main focus in metabolism research area is the biological regulatory mechanism and its role in obesity, diabetes, cardiovascular diseases, and cancer. The unique collection of 1040 small chemicals targeting metabolism diseases will provide the support for metabolism research and related drug screening.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 12480.00
250 μL * 10 mM (in DMSO) 20800.00
1 mg 20800.00
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Product Description

  • A unique collection of 1040 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or CFDA;
  • Covers various major targets including CYP, FAAH, IDO, MAO, etc., in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc.; Effective tool for cell metabolism research;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
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Library Composition

Dehydrogenase (50)
PDE (41)
P450 (39)
PPAR (39)
Glucocorticoid Receptor (38)
GR (38)
Vitamin (31)
COX (28)
MAO (26)
Potassium Channel (21)
Carbonic Anhydrase (19)
AChR (18)
HSP (18)
RAAS (17)
Phospholipase (17)
HIV Protease (14)
DNA/RNA Synthesis (13)
NADPH (12)
Retinoid Receptor (12)
Transferase (12)
Glucokinase (11)
Autophagy (11)
DHFR (10)
Casein Kinase (10)
HIF (10)
Proteasome (10)
Thrombin (9)
HMG-CoA Reductase (9)
GPR (9)
NF-κB (9)
Lipoxygenase (9)
Lipase (8)
Lipid (8)
Cysteine Protease (8)
DPP-4 (8)
Adrenergic Receptor (8)
ROS (8)
Serine Protease (8)
transporter (7)
AhR (7)
Estrogen/progestogen Receptor (7)
MMP (7)
MRP (7)
Factor Xa (7)
FXR (7)
HIF/HIF Prolyl-Hydroxylase (6)
Histamine Receptor (6)
HCV Protease (6)
IDO (6)
FAAH (6)
5-HT Receptor (6)
Wnt/beta-catenin (6)
SGLT (6)
Reductase (6)
Sodium Channel (5)
Tyrosinase (5)
Reverse Transcriptase (5)
PKA (5)
AMPK (5)
Annexin A (5)
CAT (5)
Calcium Channel (5)
IL Receptor (5)
Liver X Receptor (5)
MPO (5)
Fatty Acid Synthase (5)
GluR (5)
HDAC (4)
Hydroxylase (4)
Microtubule Associated (4)
NOS (4)
LDL (4)
CDK (4)
CETP (4)
Cannabinoid Receptor (4)
Antifection (4)
PKC (4)
PKM (4)
ribosome (4)
TNF (4)
UGT (4)
VEGFR (4)
ROR (3)
SGK (3)
Proton pump (3)
PI3K (3)
ATPase (3)
BCL (3)
Bcr-Abl (3)
Antibacterial (3)
ABC (3)
Akt (3)
Dopamine Receptor (3)
DNA Alkylation (3)
cholecystokinin (3)
Caspase (3)
LTR (3)
Integrin (3)
IκB/IKK (3)
HBV (3)
Glutathione reductase (3)
GSK-3 (3)
Ferroptosis (3)
Glucagon Receptor (3)
ERK (2)
GABA Receptor (2)
FLT (2)
GPCR19 (2)
HSV (2)
NMDAR (2)
P2 Receptor (2)
OAT (2)
Opioid Receptor (2)
mTOR (2)
NADPH-oxidase (2)
NAMPT (2)
c-RET (2)
Chloride channel (2)
Decarboxylase (2)
Endogenous Metabolite (2)
ACAT (2)
Acetyl-CoA Carboxylase (2)
Acyltransferase (2)
Adenosine Receptor (2)
Amino Acids and Derivatives (2)
Aminopeptidase (2)
Antioxidant (2)
Apoptosis (2)
Phosphatase (2)
p53 (2)
PDK (2)
PED (2)
PERK (2)
Sirtuin (2)
Somatostatin (2)
TAM Receptor (2)
TRP/TRPV Channel (2)
Topoisomerase (2)
Thyroid hormone receptor(THR) (1)
Tyrosine Kinases (1)
Trk receptor (1)
Vasopressin Receptor (1)
VDA (1)
Telomerase (1)
TGF-beta/Smad (1)
Thioredoxin (1)
Src (1)
Syk (1)
S6 Kinase (1)
P-gp (1)
PAI-1 (1)
Parasite (1)
PARP (1)
Platelet aggregation (1)
Phosphorylase (1)
PDGFR (1)
Pim (1)
PTEN (1)
Prostaglandin Receptor (1)
ROCK (1)
Raf (1)
RAR/RXR (1)
Ras (1)
Arginase (1)
Aromatase (1)
ASK (1)
ATM/ATR (1)
ATP Citrate Lyase (1)
Antiviral (1)
Antifungal (1)
BMI-1 (1)
Bombesin Receptor (1)
Aurora Kinase (1)
BACE (1)
Antibiotic (1)
Androgen Receptor (1)
ALK (1)
Epigenetic Reader Domain (1)
EGFR (1)
Dehydrogenase inhibitor (1)
DNA gyrase (1)
DNA-PK (1)
cell cycle arrest (1)
c-Met/HGFR (1)
c-Myc (1)
CCR (1)
CaMK (1)
Carboxypeptidase(CPG2) (1)
Neprilysin (1)
Na-K-Cl cotransporter (1)
p38 MAPK (1)
NPC1L1 (1)
Nrf2 (1)
JAK (1)
Influenza Virus (1)
LPA Receptor (1)
Monocarboxylate transporter (1)
Mdm2 (1)
MEK (1)
Melatonin Receptor (1)
Hydrogenase (1)
IAP (1)
Hedgehog/Smoothened (1)
Hexokinase (1)
Histone Demethylase (1)
Histone Methyltransferase (1)
GSNOR (1)
GST (1)
Free radical scavengers (1)
Gap Junction Protein (1)