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Compound Libraries Anti-Metabolism Disease Compound Library

Anti-Metabolism Disease Compound Library

Catalog No. L5200
  Library Compound List   Excel SDF

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of the cells and the organism, including catabolism and anabolism, and is one way the body maintains homeostasis. The main focus in metabolism research area is the biological regulatory mechanism and its role in obesity, diabetes, cardiovascular diseases, and cancer. The unique collection of 1471 small chemicals targeting metabolism diseases will provide the support for metabolism research and related drug screening.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 17400.00
250 μL * 10 mM (in DMSO) 29000.00
1 mg 29000.00
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Product Description

  • A unique collection of 1471 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or CFDA;
  • Covers various major targets including CYP, FAAH, IDO, MAO, etc., in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc.; Effective tool for cell metabolism research;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L5200)

Library Composition

Endogenous Metabolite (206)
Dehydrogenase (83)
P450 (81)
PDE (74)
PPAR (72)
Glucocorticoid Receptor (41)
MAO (40)
GR (39)
Vitamin (38)
COX (37)
HSP (36)
Glucokinase (30)
Carbonic Anhydrase (29)
Lipoxygenase (27)
AMPK (26)
Phospholipase (25)
Potassium Channel (24)
Retinoid Receptor (20)
Casein Kinase (20)
AChR (19)
RAAS (18)
NADPH (17)
NF-κB (17)
Transferase (17)
Autophagy (16)
AhR (15)
Phosphatase (15)
ROCK (14)
Calcium Channel (14)
HMG-CoA Reductase (14)
IDO (14)
FXR (14)
FAAH (13)
HIV Protease (13)
Adrenergic Receptor (13)
Reductase (13)
Mitochondrial Metabolism (12)
GPR (12)
HIF (12)
DPP-4 (12)
IL Receptor (11)
Liver X Receptor (10)
Lipase (10)
HIF/HIF Prolyl-Hydroxylase (10)
Hydroxylase (10)
Fatty Acid Synthase (10)
Apoptosis (10)
DHFR (10)
ROS (10)
ROR (9)
SGLT (9)
DNA/RNA Synthesis (9)
5-HT Receptor (9)
Factor Xa (9)
Estrogen/progestogen Receptor (8)
Histamine Receptor (8)
Lipid (8)
CDK (8)
Serine Protease (8)
transporter (8)
Proteasome (8)
PKA (8)
MMP (8)
PKC (7)
PKM (7)
Thrombin (7)
TNF (7)
Wnt/beta-catenin (7)
UGT (7)
Sodium Channel (7)
VEGFR (6)
Tyrosinase (6)
PAI-1 (6)
NAMPT (6)
MPO (6)
NOS (6)
Cysteine Protease (6)
Aminopeptidase (6)
Antifection (6)
ERK (6)
HCV Protease (6)
HDAC (5)
GSK-3 (5)
IκB/IKK (5)
ATPase (5)
Akt (5)
Acyltransferase (5)
DNA Alkylation (5)
CETP (5)
Caspase (5)
p38 MAPK (5)
Opioid Receptor (5)
MRP (5)
Phosphorylase (5)
Reverse Transcriptase (5)
SGK (5)
TRP/TRPV Channel (4)
ribosome (4)
PI3K (4)
PARP (4)
PED (4)
mTOR (4)
Neprilysin (4)
Microtubule Associated (4)
CAT (4)
Cannabinoid Receptor (4)
Dopamine Receptor (4)
Annexin A (4)
BCL (4)
Bcr-Abl (4)
LDL (4)
GPCR19 (4)
GluR (4)
GABA Receptor (3)
Ferroptosis (3)
JNK (3)
Integrin (3)
HBV (3)
Antibacterial (3)
Acetyl-CoA Carboxylase (3)
ABC (3)
c-Met/HGFR (3)
Decarboxylase (3)
ATP Citrate Lyase (3)
CCR (3)
Chloride channel (3)
Carboxypeptidase(CPG2) (3)
P2 Receptor (3)
p53 (3)
Nrf2 (3)
Reactive Oxygen Species (3)
P-gp (3)
Prostaglandin Receptor (3)
Vasopressin Receptor (3)
Xanthine Oxidase (3)
Topoisomerase (3)
Serine/threonin kinase (3)
Src (3)
Sirtuin (3)
TAM Receptor (3)
TGF-beta/Smad (2)
Syk (2)
SIK (2)
STAT (2)
Thyroid hormone receptor(THR) (2)
Trk receptor (2)
S6 Kinase (2)
PERK (2)
PDK (2)
OAT (2)
NPC1L1 (2)
OX Receptor (2)
Neurokinin receptor (2)
NADPH-oxidase (2)
MLK (2)
MEK (2)
cell cycle arrest (2)
CaMK (2)
Dehydrogenase inhibitor (2)
c-RET (2)
ACAT (2)
Adenosine Receptor (2)
Adiponectin receptor (2)
Antibiotic (2)
Androgen Receptor (2)
Amino Acids and Derivatives (2)
Aurora Kinase (2)
Antioxidant (2)
Antiviral (2)
Hexokinase (2)
Histone Demethylase (2)
HSV (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
JAK (2)
LTR (2)
FLT (2)
EGFR (2)
Electron transport (2)
Epigenetic Reader Domain (2)
Glutathione Peroxidase (2)
Glutathione reductase (2)
Gap Junction Protein (1)
GSNOR (1)
GST (1)
GRK (1)
Hedgehog/Smoothened (1)
HER (1)
Epoxide Hydrolase (1)
Endothelin Receptor (1)
DprE1 (1)
Free radical scavengers (1)
FABP (1)
LPA Receptor (1)
LRRK2 (1)
Isocitrate Dehydrogenase (IDH) (1)
Hydrogenase (1)
IAP (1)
IGF-1R (1)
iGluR (1)
hCE (1)
Histone Acetylation (1)
Antifungal (1)
Arginase (1)
ASK (1)
ATM/ATR (1)
BACE (1)
BMI-1 (1)
Bombesin Receptor (1)
Bradykinin Receptor (1)
ALK (1)
Anion Exchanger (1)
aconitase (1)
CSF-1R (1)
CPT (1)
DNA-PK (1)
DNA gyrase (1)
DNA Methyltransferase (1)
DNA (1)
cholecystokinin (1)
c-Kit (1)
c-Fms (1)
CFTR (1)
Melatonin Receptor (1)
Mdm2 (1)
Monocarboxylate transporter (1)
N-Acetylglucosaminyltransferase (1)
MT Receptor (1)
NMDAR (1)
NO Synthase (1)
NOD (1)
Norepinephrine (1)
PAK (1)
Parasite (1)
PDGFR (1)
Pim (1)
Platelet aggregation (1)
Proton pump (1)
PTP1B (1)
RAR/RXR (1)
Tyrosine Kinases (1)
TLR (1)
Transaminase (1)
Stearoyl-CoA Desaturase (SCD) (1)
stilbene oxidase (1)
Thioredoxin (1)
Telomerase (1)