Cart
Compound Libraries Angiogenesis related Compound Library

Angiogenesis related Compound Library

Catalog No. L4800
  Library Compound List   Excel SDF

Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in the formation of granulation tissue. However, uncontrolled angiogenesis underlies many deadly and debilitating conditions, including cancer, skin diseases, immune disorders, diabetic ulcers, cardiovascular disease, stroke, critical limb ischemia, and many others. Therefore, angiogenesis has become an attractive target for combating diseases characterized by either poor vascularization or abnormal vasculature. For example, angiogenesis plays a critical role in the growth of cancer. Tumors induce blood vessel growth (angiogenesis) by secreting various growth factors (e.g. VEGF) and proteins which induce capillary growth into the tumor, providing it with oxygen and nutrients. Angiogenesis is also required for the spread of a tumor, or metastasis. Therefore, angiogenesis inhibitors can be used to treat cancer. In addition, proangiogenic therapies are being explored as options to treat ischemic cardiovascular diseases by formation of “natural bypasses”—that is, collateral vessels.

The TargetMol’s Angiogenesis related Compound Library, a unique collection of angiogenesis related compounds, can be used for research in angiogenesis and related drug discovery.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 7590.00
250 μL * 10 mM (in DMSO) 11310.00
1 mg 11310.00
Top Publication Citing Use of Targetmol Products
Request Library

Product Description

  • A unique collection of 378 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
  • Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc.;
  • Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice.
Request Library Compound List (L4800)

Library Composition

EGFR (76)
VEGFR (72)
Src (44)
Bcr-Abl (43)
PDGFR (43)
JAK (42)
FLT (41)
FGFR (38)
c-Kit (32)
ALK (30)
RAAS (18)
Tyrosine Kinases (18)
HER (15)
c-Met/HGFR (14)
BTK (12)
FAK (12)
Raf (12)
c-RET (11)
HIF (11)
Syk (10)
IGF-1R (9)
Aurora Kinase (9)
CDK (8)
BCL (7)
TAM Receptor (7)
Thrombin (6)
PKC (6)
PKA (5)
Chk (5)
Trk receptor (5)
PYK2 (4)
PPAR (4)
COX (4)
c-Fms (4)
CSF-1R (4)
Ephrin Receptor (3)
Factor Xa (3)
GSK-3 (3)
Casein Kinase (3)
Adrenergic Receptor (3)
Potassium Channel (3)
PI3K (3)
Microtubule Associated (3)
mTOR (3)
IκB/IKK (3)
ROS (3)
S1P Receptor (3)
STAT (3)
TNF (3)
Tyrosinase (2)
VDA (2)
ROCK (2)
Tie-2 (2)
S6 Kinase (2)
Serine Protease (2)
Protease-activated Receptor (2)
Integrin (2)
LDL (2)
MAPK (2)
NADPH (2)
MRP (2)
PDE (2)
AChR (2)
ACK (2)
Hck (2)
DNA-PK (2)
ERK (2)
Dehydrogenase (2)
DNA (1)
Cysteine Protease (1)
Estrogen/progestogen Receptor (1)
FAAH (1)
Epigenetic Reader Domain (1)
HDAC (1)
Hedgehog/Smoothened (1)
Adenosine Receptor (1)
Akt (1)
Antiviral (1)
ATPase (1)
Carbonic Anhydrase (1)
p38 MAPK (1)
MLK (1)
Monoamine Transporter (1)
Pim (1)
PDK (1)
Platelet aggregation (1)
Mdm2 (1)
MEK (1)
MAO (1)
JNK (1)
IL Receptor (1)
Gap Junction Protein (1)
GPR (1)
HIF/HIF Prolyl-Hydroxylase (1)
Histamine Receptor (1)
PTEN (1)
Prostaglandin Receptor (1)
Serine/threonin kinase (1)
Sodium Channel (1)
TGF-beta/Smad (1)
Vitamin (1)