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Home > Stem Cells > TGF/beta/Smad > EW-7197
EW-7197  
Catalog No. T6496    CAS 1352608-82-2
Pack Size
Availability
Price/USD
Quantity
2mg
In stock
77.00
5mg
In stock
111.00
10mg
In stock
187.00
25mg
In stock
374.00
50mg
In stock
578.00
100mg
In stock
808.00
1g
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0.00
5g
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0.00
10mM * 1mL (in DMSO)
In stock
97.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.81% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

Vactosertib is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potential antineoplastic activity.

Target:
ALK6; ALK5; ALK4; ALK3; ALK2; ALK1;
Research Area:
Immunology
Chemical Information:
Molecular Weight 399.42
Formula C22H18FN7
CAS Number 1352608-82-2
Solubility DMSO:73 mg/mL (182.8 mM);Ethanol:40 mg/mL (100.1 mM);Water:<1 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
  • The compound is not included in our libraries at this moment.
Product Recommendations
  • LDN-193189 hydrochloride, LDN193189 hydrochloride is a selective BMP type I receptor kinases inhibitor.
  • RepSox, RepSox is a potent and selective of the TGFβR-1/ALK5 inhibitor.

 

Reference

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