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BIX02189  
Catalog No. T2416    CAS 1094614-85-3
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5mg
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10mg
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25mg
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5g
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10mM * 1mL (in DMSO)
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242.00
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Documents and Quality Management
Purity:98.00% COA Datasheet HNMR MSDS
Biological Activity:

Product Description:

BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.

Target:
TGFβ; MEK5; MEK1; JNK1; ERK5; ERK1;
Research Area:
Other
Chemical Information:
Molecular Weight 440.54
Formula C27H28N4O2
CAS Number 1094614-85-3
Solubility DMSO:56 mg/mL (127.1 mM);Ethanol:74 mg/mL (168 mM);Water:<1 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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