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Home > Tyrosine Kinase/Adaptors > EGFR > AZD3759
AZD3759  
Catalog No. T3659    CAS 1626387-80-1
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5mg
In stock
51.00
10mg
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68.00
25mg
In stock
86.00
50mg
In stock
128.00
100mg
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204.00
1g
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0.00
5g
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0.00
10 mM * 1 mL (in DMSO)
In stock
56.00
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Documents and Quality Management
Purity:99.36% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

AZD3759 is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectively.

Target:
EGFR;
Research Area:
Cancer
Chemical Information:
Molecular Weight 459.9
Formula C22H23ClFN5O3
CAS Number 1626387-80-1
Solubility Ethanol:44 mg/mL warming (95.67 mM);DMSO:91 mg/mL (197.87 mM);Water:<1 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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