info@targetmol.com    Tel: (857) 239-0968 / (617) 419-7131
Home > Chromatin/Epigenetic > Sirt/Sirtuin > Splitomicin
Splitomicin  
Catalog No. T6678    CAS 5690-03-9
Pack Size
Availability
Price/USD
Quantity
10mg
In Stock
72.00
10mM * 1mL (in DMSO)
In Stock
95.00
50mg
In Stock
285.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:98.00% COA Datasheet
Biological Activity:

Product Description:

Splitomicin is a selective NAD(+)-dependent histone deacetylase Sir2p inhibitor with IC50 of 60 μM, showing a higher activity in a cell-based assay.

Target:
Sir2p;
Research Area:
Cancer
Chemical Information:
Molecular Weight 198.22
Formula C13H10O2
CAS Number 5690-03-9
Solubility DMSO: 39mg/ml(196.75 mM);Water: <1mg/ml;Ethanol: 39mg/ml(196.75 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
  • The compound is not included in our libraries at this moment.
Product Recommendations
  • SirReal2, SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.
  • Sirtinol, Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM, respectively.
  • SRT2104 (GSK2245840), SRT2104 (GSK2245840) is a selective SIRT1 activator involved in the regulation of energy homeostasis...
  • AGK2, AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM.
  • Fisetin, Extracted from Rhus succedanea L;Store the product in sealed, cool and dry condition.

 

Reference

If you have additional questions, Please send us a message. * Required