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Home > Immunology/Inflammation > TGF/beta/Smad > Pirfenidone
Pirfenidone  
Catalog No. T2386    CAS 53179-13-8
Pack Size
Availability
Price/USD
Quantity
50mg
In stock
27.00
100mg
In stock
51.00
500mg
In stock
85.00
1000mg
In stock
128.00
10 mM * 1 mL (in DMSO)
In stock
56.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.90% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis.

Target:
TGF-β;
Research Area:
Chemical Information:
Molecular Weight 185.22
Formula C12H11NO
CAS Number 53179-13-8
Solubility water:3.7 mg/mL (20 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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