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Home > Cell cycle/Check point > Chk > PF-477736
PF-477736  
Catalog No. T6028    CAS 952021-60-2
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5mg
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120.00
10mg
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170.00
25mg
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315.00
50mg
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538.00
1g
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5g
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10 mM * 1 mL (in DMSO)
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202.00
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Documents and Quality Management
Purity:98.34% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

PF-477736 is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.

Target:
YES; VEGFR2; Fms; Chk2; Chk1;
Research Area:
Cancer
Chemical Information:
Molecular Weight 419.48
Formula C22H25N7O2
CAS Number 952021-60-2
Solubility DMSO:31.5 mg/mL (75 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
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Reference

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