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Home > Immunology/Inflammation > TGF/beta/Smad > PF-06463922
PF-06463922  
Catalog No. T3061    CAS 1454846-35-5
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2mg
In stock
27.00
5mg
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51.00
10mg
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77.00
25mg
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128.00
50mg
In stock
204.00
100mg
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357.00
1g
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0.00
5g
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0.00
10mM * 1mL (in DMSO)
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56.00
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Documents and Quality Management
Purity:99.50% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

PF-06463922 is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. Phase 1.

Target:
FAK2; FES; FER; LTK; ALLK; ROS1;
Research Area:
Cancer
Chemical Information:
Molecular Weight 406.41
Formula C21H19FN6O2
CAS Number 1454846-35-5
Solubility DMSO: 81mg/ml(199.31 mM);Water: <1mg/ml;Ethanol: 30mg/ml(73.82 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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