sales@targetmol.com (US) / info@targetmol.com    Tel: (781) 999-4286 / (781) 999-5354
Home > Neuroscience > BACE > LX2343
LX2343  
Catalog No. T4398    CAS 333745-53-2
Pack Size
Availability
Price/USD
Quantity
1mg
In stock
40.00
2mg
In stock
71.00
5mg
In stock
132.00
10mg
In stock
202.00
25mg
In stock
366.00
50mg
In stock
598.00
100mg
In stock
951.00
200mg
In stock
1415.00
1g
Get quote
0.00
5g
Get quote
0.00
10mM * 1mL (in DMSO)
In stock
144.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.92% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.

Target:
BACE1; Autophagy; Aβ; PI3K;
Research Area:
Neurological Disease
Chemical Information:
Molecular Weight 474.912
Formula C22H19ClN2O6S
CAS Number 333745-53-2
Solubility DMSO: ≥ 155 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
  • The compound is not included in our libraries at this moment.
Product Recommendations
  • Curculigoside, 1. Curculigoside can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFS...
  • Albiflorin, 1. Albiflorin has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuropro...
  • Sesamolin, 1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-in...
  • NotoginsenosideFa, 1. Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuro...
  • Stearic acid, 1. Stearic Acid can reduce metastatic tumor burden. 2. Stearic Acid leads to dramatically reduced ...

 

Reference

If you have additional questions, Please send us a message. * Required