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product7/INH1.html

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  • Inhibitors & Agonists
    147
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    26
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Rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine
T62750L2738485-99-7In house
rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ≤ 0.05 μM and an E.max value of > 250 μM for TREM2.
  • $320
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GLP-1(7-36), amide
T3984107444-51-9
GLP-1(7-36) amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient intake. It binds to the GLP-1 receptor in the pancreas, enhancing insulin secretion from pancreatic β-cells and increasing insulin expression, thereby exhibiting antidiabetic effects.
  • $185
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TargetMol | Citations Cited
5-HT6/7 antagonist 1
T61807131999-28-5In house
5-HT6 7 antagonist 1 is a dual 5-HT6 7 2A and D2 receptor antagonist used in the study of dementia and Alzheimer's disease.
  • $700 TargetMol
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7-Methoxy-1-tetralone
Fr122756836-19-7
7-Methoxy-1-tetralone may have insecticidal activity.
  • $29
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Potassium 7-hydroxy-1-naphthalenesulfona
TN705030252-40-5
Potassium 7-hydroxy-1-naphthalenesulfona (2-Naphthol-8-sulfonic Acid Potassium Salt) is naturally present in the fruit of the Rubiaceae gardenia, the flowers of the Iridaceae crocus, and the flowers and leaves of the Scrophulariaceae Scrophulariaceae.
  • $30
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7-Methoxy-1-naphthaleneacetic acid
T98976836-22-2
7-Methoxy-1-naphthaleneacetic acid is an inhibitor of auxin action in plants. 7-Methoxy-1-naphthaleneacetic acid inhibits polar auxin transport and tropic responses associated with asymmetric auxin distribution in Arabidopsis and maize. 7-Methoxy-1-naphthaleneacetic acid inhibits auxin transport mediated by AUX1, PIN, and ABCB proteins expressed in yeast.
  • $29
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Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
T66256503614-91-3
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagulation factor Xa, and it can be used in the study of thrombophlebitis, atherosclerosis, cerebral embolism, stroke and pulmonary embolism.
  • $35
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1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea
T601242379727-88-3In house
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-α agonistic compound, could induce cells to secrete TNF- α.
  • $117
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1-(7-carbamimidamidoheptyl)guanidine 2HCl
T500922193061-39-9
1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerative diseases.
  • $86
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3-​Phenyl-​N-​[1-​(phenylmethyl)​-​4-​piperidinyl]​-tricyclo[3.3.1.13,​7]​decane-​1-​carboxamide
T85011252187-41-9
3- Phenyl- N- [1- (phenylmethyl) - 4- piperidinyl] -tricyclo[3.3.1.13, 7] decane- 1- carboxamide with antiviral activity against Ebola virus that targets the surface-exposed glycoprotein and inhibits viral entry into host cells. In vitro studies in Vero cells revealed the compound inhibits the viral replication with EC50 of 0.38 μM.
  • $80
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Substance P (1-7) 2TFA(68060-49-1(free base))
T7675
Substance P (1-7) 2TFA(68060-49-1(free base)) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects
  • $48
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(S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide
T601861934246-20-4In house
MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.
  • $117
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Nociceptin (1-7) acetate
T23076L
Nociceptin (1-7) acetate is a potent agonist of opioid receptor-like 1 (ORL1) receptor. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia and has antinociceptive activity.
  • $326
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Hemokinin 1 (human) acetate(491851-53-7 free base)
TP1899L1
Hemokinin 1 (human) acetate is an endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B
  • $101
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Orphanin FQ(1-11) acetate(178249-41-7 free base)
TP1882L1
Orphanin FQ(1-11) acetate(178249-41-7 free base) is a peptide fragment containing amino acids 1-11 of Nociceptin. Orphanin FQ(1-11) acetate(178249-41-7 free base) is a potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM) and displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Orphanin FQ(1-11) acetate(178249-41-7 free base) displays analgesic properties in CD-1 mice.
  • $162
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6-chloro-1-ethyl-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
T5010570458-73-0
6-chloro-1-ethyl-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a compound used as a molecular structural unit for pefloxacin impurities.
  • $58
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Angiotensin 1/2 (5-7) acetate
T22574L
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It
  • $29
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3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one
T501021799561-19-5
3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one is a compound that has been extensively investigated for the treatment of a variety of disorders including tumors, Alzheimer's and Parkinson's diseases, anti-inflammatory drugs, and analgesic agents.
  • $97
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2-(7-Methoxy-1-naphthyl)ethylamine HCl
T9898139525-77-2
2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride is the impurity of Agomelatine, an antidepressant.
  • $30
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7-Methoxy-1-naphthylacetonitrile
T9896138113-08-3
7-Methoxy-1-naphthylacetonitrile is one of the impurities of agomelatine, an antidepressant.
  • $30
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GLP-1(7-37) acetate(106612-94-6 free base)
TP13761450806-98-0
Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
  • $113
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7-Chloro-4-(piperazin-1-yl)quinoline
Fr13587837-52-5
7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry, exhibiting diverse pharmacological profiles either alone or as a hybrid with other active pharmacophores. It is a potent sirtuin inhibitor, also inhibiting serotonin uptake (IC50 of 50 μM), and demonstrates antimalarial activity on D10 and K1 strains of P. falciparum with IC50 values of 1.18 μM and 0.97 μM, respectively [1].
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Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha
T81326138989-37-4
Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha is a flavonol glycoside with no significant inhibitory effects on lipid accumulation induced by albumin oleate.
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(Z)-7-Dodecen-1-ol
TN798220056-92-2
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Cecropin A (1-7)-Melittin A (2-9)
T76468157606-25-2
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with broad-spectrum activity against both Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial properties, without the adverse hemolytic effects commonly associated with bee venom peptides [1].
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1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane
TN5758182369-54-6
1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane is a natural product for research related to life sciences. The catalog number is TN5758 and the CAS number is 182369-54-6.
  • $740
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1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine
TNU03872389988-22-9
Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosides
  • Inquiry Price
7-10 days
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7-Octyn-1-ol
T64953871-91-0
7-Octyn-1-ol is a useful organic compound for research related to life sciences. The catalog number is T64953 and the CAS number is 871-91-0.
    7-10 days
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    1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
    T65490170791-09-0
    1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T65490 and the CAS number is 170791-09-0.
      7-10 days
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      7-Hydroxy-beta-carboline-1-propionic acid
      T125336
      7-Hydroxy-beta-carboline-1-propionic acid is a useful organic compound for research related to life sciences and the catalog number is T125336.
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      1-Cyclopropyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
      T66422103460-89-5
      1-Cyclopropyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66422 and the CAS number is 103460-89-5.
        7-10 days
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        L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside
        TN144788700-35-0
        Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside is a natural product from Radix ophiopogonis.
        • $250
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        HIV-1 protease-IN-7
        T749422916441-36-4
        HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor with an IC50 of 3.52 nM and an EC50 of 37 nM [1].
        • Inquiry Price
        8-10 weeks
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        1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
        T66423112811-57-1
        1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66423 and the CAS number is 112811-57-1.
          7-10 days
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          (11aS)-N,N-Diethyl-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-amine
          T64499477559-80-1
          (11aS)-N,N-Diethyl-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-amine is a useful organic compound for research related to life sciences and the catalog number is T64499.
            7-10 days
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            (R)-tert-Butyl (4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate
            T65597486460-23-5
            (R)-tert-Butyl (4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate is a useful organic compound for research related to life sciences and the catalog number is T65597.
              7-10 days
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              (11aR)-N,N-Bis((S)-1-phenylethyl)-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-amine
              T64794656233-47-5
              (11aR)-N,N-Bis((S)-1-phenylethyl)-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-amine is a useful organic compound for research related to life sciences and the catalog number is T64794.
                7-10 days
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                Apigenin 7-[rhamnosyl-(1->2)-galacturonide]
                T126160
                Apigenin 7-[rhamnosyl-(1->2)-galacturonide] is a useful organic compound for research related to life sciences and the catalog number is T126160.
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                3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
                T64758
                3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a useful organic compound for research related to life sciences and the catalog number is T64758.
                  7-10 days
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                  7-epi Maresin 1
                  T370011268720-66-6
                  7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.
                  • $193
                  35 days
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                  (11aS)-N,N-Diisopropyl-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-amine
                  T64516477559-83-4
                  (11aS)-N,N-Diisopropyl-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-amine is a useful organic compound for research related to life sciences and the catalog number is T64516.
                    7-10 days
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                    13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide
                    TN2608126829-66-1
                    13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide is a natural product from Artemisia myriantha.
                    • $550
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                    Angiotensin Fragment 1-7 (acetate)
                    T22575
                    Angiotensin Fragment 1-7 is a type 1 angiotensin II receptor agonist. In the renin-angiotensin system, angiotensin I is cleaved by the angiotensin-converting enzyme to form angiotensin II, which has effects on fluid and electrolyte, as well as homeostasis
                    • $306
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                    (1R,4aS,10aR)-methyl 7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate
                    T672001235-74-1
                    (1R,4aS,10aR)-methyl 7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate is a natural product for research related to life sciences. The catalog number is T67200 and the CAS number is 1235-74-1.
                      7-10 days
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                      (11aR)-5-(4,5,6,7-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine
                      T645131361055-04-0
                      (11aR)-5-(4,5,6,7-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine is a useful organic compound for research related to life sciences and the catalog number is T64513.
                        7-10 days
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                        GLP-1(7-36), amide acetate
                        TP11411119517-19-9
                        GLP-1(7-36) Acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.
                        • $198
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                        Bradykinin (1-7)
                        TP121023815-87-4
                        Bradykinin (1-7), an amino-truncated peptide derived from Bradykinin, is a metabolite formed through enzymatic cleavage by endopeptidase.
                        • $121
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                        7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one
                        TN3218100667-52-5
                        7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may provide new insights on drug discovery of Alzheimer's disease (AD).
                        • $540
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