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Home > Tyrosine Kinase/Adaptors > EGFR > EGF816
EGF816  
Catalog No. T3506    CAS 1508250-71-2
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5mg
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118.00
10mg
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249.00
25mg
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398.00
50mg
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557.00
100mg
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840.00
1g
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5g
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10 mM * 1 mL (in DMSO)
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175.00
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Documents and Quality Management
Purity:98.63% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.

Target:
EGFR (mutant);
Research Area:
Others
Chemical Information:
Molecular Weight 495.02
Formula C26H31ClN6O2
CAS Number 1508250-71-2
Solubility DMSO:92 mg/mL (185.9 mM);Ethanol:92 mg/mL (185.9 mM);Water:<1 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
  • The compound is not included in our libraries at this moment.
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Reference

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