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Home > Metabolism > Dehydrogenase > Dicumarol
Dicumarol  
Catalog No. T0809    CAS 66-76-2
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50mg
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23.00
100mg
In stock
43.00
200mg
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64.00
1g
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0.00
5g
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0.00
10 mM * 1 mL (in DMSO)
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47.00
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Documents and Quality Management
Purity:99.90% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

Dicumarol?is a?hydroxycoumarin?originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities.?Dicumarol?is a competitive inhibitor of?vitamin K epoxidereductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.

Target:
VKOR; QOR; NAD(P)H DH1;
Research Area:
Metabolism system
Chemical Information:
Molecular Weight 336.29
Formula C19H12O6
CAS Number 66-76-2
Solubility DMSO:62 mg/mL (184.4 mM);Ethanol:62 mg/mL (184.4 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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