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CHIR-124  
Catalog No. T6350    CAS 405168-58-3
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2mg
In stock
45.00
5mg
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85.00
10mg
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145.00
25mg
In stock
278.00
50mg
In stock
510.00
100mg
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723.00
1g
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0.00
5g
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0.00
10 mM * 1 mL (in DMSO)
In stock
94.00
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Documents and Quality Management
Purity:96.33% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2,000-fold selectivity against Chk2, 500- to 5,000-fold less activity against Cdc2 and CDK2/4.

Target:
PDGFR; GSK-3; Fyn; FLT3; Chk1;
Research Area:
Cancer
Chemical Information:
Molecular Weight 419.91
Formula C23H22ClN5O
CAS Number 405168-58-3
Solubility DMSO:7 mg/mL (16.67 mM);Ethanol:<1 mg/mL;Water:<1 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
  • The compound is not included in our libraries at this moment.
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Reference

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