sales@targetmol.com (US) / info@targetmol.com    Tel: (781) 999-4286 / (857) 239-0968
Home > Membrane transporter/Ion Channel > TRP/TRPV > AMG-517
AMG-517  
Catalog No. T6379    CAS 659730-32-2
Pack Size
Availability
Price/USD
Quantity
5mg
In stock
101.00
10mg
In stock
140.00
25mg
In stock
265.00
50mg
In stock
485.00
1g
Get quote
0.00
5g
Get quote
0.00
10mM * 1mL (in DMSO)
In stock
111.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.85% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.

Target:
TRPV1;
Research Area:
Nervous system
Chemical Information:
Molecular Weight 430.4
Formula C20H13F3N4O2S
CAS Number 659730-32-2
Solubility DMSO:43 mg/mL (100 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
Product Recommendations
  • (-)-MK 801 Maleate, MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat...
  • WIN 55,212-2 Mesylate, WIN 55,212-2 (Mesylate) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis of 6...
  • Edonerpic maleate, Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ).
  • DAMGO TFA (78123-71-4(Free base)), Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adeny...
  • SR17018, SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.

 

Reference

If you have additional questions, Please send us a message. * Required