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TGF--beta-Smad
Cat.No. Product Name Information Area
T1944 LDN-214117 LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold se... Immunology
T1943 ML347 ML347(DN193719) is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM; sho... Other
T1942 DMH-1 DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5 nM for ALK1/2... Other
T1936 CH5424802 CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive... Other
T1935 LDN193189 LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcription... Other
T1914 K02288 K02288 is a novel small molecule inhibitor of ALK1/2/3/6 with IC50s of 1.8/1.1/34.4/6... Other
T1900 LDN-212854 LDN-212854 is a novel BMP inhibitor that exhibits substantially greater selectivity f... Other
T1800 GW788388 GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibit... Other
T1791 LDK378(Ceritinib) Ceritinib is an orally available inhibitor of the receptor tyrosine kinase activity o... Cancer
T1763 SB 525334 SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 1... Other
T1748 Kartogenin Kartogenin is an activator of the smad4/smad5 pathway, and promotes the selective dif... Immunology
T1726 SB-431542hot SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM in a cell-fre... Immunology
T1661 Crizotinibhot Crizotinib an inhibitor of receptor tyrosine kinase for the treatment of non-small ce... Cancer
T6337 RepSox RepSox is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and... Immunology
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