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p53
Cat.No. Product Name Information Area
T4414 PRIMA-1Met PRIMA-1MET restores wild-type conformation and function to mutant p53, and triggers a... Cancer
T4361 CBL0137 hydrochloride CBL0137 activates p53 and inhibits NF-kB (EC50: 0.37/0.47 μM) in the cell-based p53 a... Cancer
T4325 COTI-2 COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the... Cancer
T4126 CBL0137 CBL0137, a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits N...
T3997 WEHI-345 WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events ... Others
T3517 RO8994 RO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule... Others
T3637 Pifithrin-β hydrobromide

Pifithrin-β hydrobromide is an inhibitor of p53; reversibly blocks p53-dependent t...

T6954 PRIMA-1 PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of huma... Others
T6910 NSC59984 NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 act... Others
T6909 NSC348884 NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apopto... others
T3375 Verbascosidenew Verbascoside is a protein kinase C inhibitor with antimicrobial, anti-inflammatory ac... Others
T3184 Kevetrin hydrochloride Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor prot... Cancer
T6210 Pifithrin-μ Pifithrin-μ is an inhibitor of p53 and HSP70, with neuroprotective and antitumor acti... Cancer
T3000 Magnolol Magnolol is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks ... Immunology
T2970 Rotenone Rotenone is a botanical insecticide that is an inhibitor of mitochondrial electron tr... Metabolism system
T2947 Indole-3-carbinol Indole-3-carbinol, a naturally occurring, orally available cleavage product of the gl... Cancer
T2707 Pifithrin hydrobromide Pifithrin-α is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-respo... Cancer
T2464 NSC319726 NSC319726, a mutant p53R175 reactivator, suppresses growth of fibroblasts that expres... Cancer
T2243 Serdemetan Serdemetan is an orally bioavailable HDM2 antagonist with potential antineoplastic ac... Cancer
T2158 Nutlin-3 Nutlin-3 is an MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50: 0.0... Other
T1919 Tenovin-1 Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects a... Cancer
T1818 Tenovin-6 Tenovin-6 is a p53 transcriptional activity agonist. Cancer
T1798 RITA RITA(NSC 652287) induced cross-links of both DNA-DNA and DNA-protein with no detectab... Other
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