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Home > p53
Cat.No. Product Name Information Area
T4361 CBL0137 hydrochloride CBL0137(CBL-0137) activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM ... Cancer
T4325 COTI-2 COTI-2 is an orally available third generation thiosemicarbazone and activator of mut... Cancer
T4126 CBL0137 CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.... cancer
T3997 WEHI-345 WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events ... Others
T3517 RO8994 RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2... Others
T3637 Pifithrin-β hydrobromide Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apop... Others
T6954 PRIMA-1 PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of huma... Others
T6910 NSC59984 NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradation a... Others
T6909 NSC348884 NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apopto... others
T3375 Verbascosidenew Verbascoside has an antimicrobial activity, notably against Staphylococcus aureus. It... Others
T3184 Kevetrin hydrochloride Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor prot... Cancer
T6210 Pifithrin-μ Pifithrin-μ is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2,... Cancer
T3000 Magnolol Magnolol is isomeric to honokiol (sc-202653). Magnolol is an anxiolytic,anti-thrombot... Immunology
T2970 Rotenone Rotenone is an odorless, colorless, crystalline ketonic chemical compound used as a b... Metabolism system
T2947 Indole-3-carbinol Indole-3-Carbinol is a naturally occurring, orally available cleavage product of the ... Cancer
T2707 Pifithrin hydrobromide Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-r... Cancer
T2464 NSC319726 NSC319726 is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing ... Cancer
T2243 Serdemetan Serdemetan(JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces ... Cancer
T2158 Nutlin-3 Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 ... Other
T1919 Tenovin-1 Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitinati... Cancer
T1818 Tenovin-6 Tenovin-6 is a small molecule activator of p53 transcriptional activity. Cancer
T1798 RITA RITA(NSC 652287) induced both DNA-protein and DNA-DNA cross-links with no detectable ... Other