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mTOR
Cat.No. Product Name Information Area
T4423 LY303511 hydrochloride LY303511 (NV-128)is a potent mTOR inhibitor
T3514 CZ415 CZ415 is a potent and highly selective mTOR inhibitor.
T3692 GNE 477 GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor. Others
T3351 CC-223 CC-223 is an orally available mTOR inhibitor with potential antitumor activity. CC-22... Cancer
T3656 PKI-402 PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with ... Others
T3153 MLN1117 MLN1117 (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM). Cancer
T3395 Timosaponin AIIInew Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC...
T6510 GDC-0349 GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 n... Cancer
T6732 WYE-687 WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; bloc... Cancer
T6730 WAY-600 WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 n... Cancer
T6731 WYE-354 WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It ... Cancer
T6100 Torin 2 Torin 2(IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold great... Cancer
T6045 Torin 1 Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold ... Cancer
T6033 Zotarolimus(ABT-578) Zotarolimus, an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM). Cancer
T6030 XL388 XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 ... Cancer
T2995 Chrysophanic Acid Chrysophanic acid is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, a... Cancer
T2706 Palomid 529 Palomid 529 has been used in trials studying the treatment of Age-Related Macular Deg... Cancer
T2619 CH5132799 CH5132799 has been used in trials studying the treatment of Solid Tumors. Cancer
T2475 KU-0063794 KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2. Other
T2434 LY 303511 LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for... Other
T2415 PP121 PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (I... Cancer
T2414 PP 242 PP 242 is a specific and ATP competitive mTOR inhibitor (IC50=8 nM). Other
T2357 GSK1059615 GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours,... Cancer
T2235 BEZ235hot

Dactolisib is an orally bioavailable imidazoquinoline targeting the phosphatidylin...

Cancer
T2145 Temsirolimus Temsirolimus is a specific mTOR inhibitor, used in the treatment of advanced renal ce... Immunology
T2144 Tacrolimus Tacrolimus is a macrolide isolated from the culture broth of a strain of Streptomyces... Immunology
T2084 ETP-46464 ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM). Other
T1970 PKI-587 Gedatolisib is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4... Other
T1961 AZD2014 AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTO... Other
T1958 AZ20 AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free... Other
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