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Raf
Cat.No. Product Name Information Area
T4301 AD80 AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTO... others
T3579 PLX8394 PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF)... cancer
T4167 B-Raf inhibitor 1 dihydrochloride B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor. Others
T4133 CCT196969 CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It a... others
T4194 CID-25014542 CID-25014542 is novel inhibitor of Raf kinases. Others
T3711 RAF709 RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-R...
T6971 RO5126766 (CH5126766) RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM,19 nM, 56 nM, a... Others
T6895 MLN2480 MLN2480 is an oral, selective pan-Raf kinase inhibitor in clinical trials. Others
T6882 LY3009120 LY03009120 is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for ... Others
T6487 Encorafenib (LGX818) LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potentia... Cancer
T6525 GW5074 GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on t... Cancer
T2624 OSI-930 OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth fact... Cancer
T2473 PLX-4720 PLX4720 is a specific and effective inhibitor of B-RafV600E (IC50=13 nM). Other
T2382 Vemurafenibhot Vemurafenib (PLX4032, RG7204) is a novel and potent B-RafV600E inhibitor (IC50 of 31 ... Cancer
T2295 SB-590885 SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay). The sel... Other
T2293 SGX-523 SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p... Cancer
T2267 BQU57 BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft... Other
T2074 B-Raf inhibitor 1 B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor. Other
T2070 CEP-32496 CEP-32496 is a highly potent inhibitor of BRAF. Other
T1953 L-779450 L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays... Other
T1903 Dabrafenib (GSK2118436)hot Dabrafenib is a selective inhibitor of mutated forms of BRAF kinase and is used alone... Cancer
T1892 Kobe2602 Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities... Other
T1886 TAK632 TAK-632 is a potent pan-Raf inhibitor. Other
T1876 Kobe0065 Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interact... Other
T1851 ZM 336372 ZM 336372 is a potent and selective c-Raf inhibitor. Other
T1845 B-Raf IN 1 B-Raf IN 1 is a B-Raf (IC50: 24 nM) and c-Raf (IC50: 25 nM) inhibitor. Other
T1792 Regorafenib Regorafenib is a Kinase Inhibitor. The mechanism of action of regorafenib is as a Pro... Cancer
T0093L Sorafenib Sorafenib is a synthetic compound targeting growth signaling and angiogenesis. Sorafe... Cancer
T0093 Sorafenib tosylate Sorafenib Tosylate is the tosylate salt of sorafenib, a synthetic compound targeting ... Cancer
T6320 GDC-0879 GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with a... Cancer
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