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PDE
Cat.No. Product Name Information Area
T4480 Vardenafil dihydrochloride Vardenafil dihydrochloride is a new type PDE inhibitor with IC50 of 0.7 and 180 nM fo... Endocrine system
T4462 Roflumilast N-oxide Roflumilast N-oxide is a PDE type 4 inhibitor.
T4285 AN-2728 AN-2728 is a Phosphodiesterase 4 Inhibitor. inflammation
T4097 Vardenafil hydrochloride trihydrate Vardenafil HCl Trihydrate is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for... Endocrine system
T3987 E 6005 E6005 is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the t... Immunology
T3465 Vesnarinone Vesnarinone (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier t... Immunology
T6983 Sildenafil Mesylate Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiestera... Others
T6548 Irsogladine Irsogladine is an anti-gastric ulcer agent that facilitates gap-junctional intercellu... Nervous system
T6462 Deltarasin Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM f... Metabolism system
T6649 S-(+)-Rolipram S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM,... Metabolism system
T6390 Anagrelide hydrochloride Anagrelide Hydrochloride(BL4162A) is a drug used for the treatment of essential throm... Metabolism system
T6445 Cilomilast Cilomilast is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammator... Metabolism system
T6644 Rolipram Rolipram is a phosphodiesterase 4 inhibitor with antidepressant properties. Metabolism system
T6054 GSK256066 GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of... Metabolism system
T6042 PF-2545920 PF-2545920, a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more t... Metabolism system
T2923 Apremilast (CC-10004) Apremilast (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-infla... Metabolism system
T2855 Icariin Icariin is a flavonol glycoside, inhibiting PDE5 and PDE4 activities. Icariin also is... Metabolism system
T2334 Avanafil Avanafil is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as t... Endocrine system
T2137 Ibudilast Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibi... Respiratory system
T2129 Zaprinast Zaprinast was an unsuccessful clinical drug candidate that was a precursor to the che... Respiratory system
T1745 TAK-063 TAK-063 is a highly effective and selective PDE10A inhibitor (IC50: 0.30 nM); Its sel... Other
T1713 IBMX 3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor... Metabolism system
T1708 Pimobendan Pimobendan is a selective inhibitor of PDE3 (IC50: 0.32 μM). Metabolism system
T1681 Aminophylline Aminophylline is a competitive nonselective phosphodiesterase inhibitor giving a bron... Respiratory system
T1618 Dipyridamole Dipyridamole is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridam... Cardiovascular System
T1398 Tadalafil Tadalafil is a carboline-based compound with vasodilatory activity. Tadalafil selecti... Endocrine system
T1265 Amrinone Amrinone is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator pro... Cardiovascular System
T1164 Sildenafil Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor, used to treat erectile dy... Endocrine system
T1112 2-(Hydroxymethyl)pyridine 2-Pyridinylmethanol is an organic compound. Other
T1096 Milrinone Milrinone?is a Phosphodiesterase 3 Inhibitor. The mechanism of action of?milrinone?is... Cardiovascular System
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