info@targetmol.com    Tel: (857) 239-0968 / (617) 419-7131
Home > JAK
JAK
Cat.No. Product Name Information Area
T7503 Upadacitinib (ABT-494)

Upadacitinib (ABT-494) is a potent and selective Janus kinase (JAK) 1 inhibitor be...

Immunity&Inflammation
T4210 SAR-20347 SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and ... cancer
T3998 Itacitinib Itacitinib (INCB039110) is an oral selective JAK1 inhibitor.Itacitinib potently inhib... Immunology
T3673 Mollugin Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by b... Others
T6933 Peficitinib (ASP015K, JNJ-54781532) Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3. Others
T6914 Oclacitinib maleate Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 9... Others
T6838 FLLL32 FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of <5 μM. Others
T6790 BMS-911543 BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1?nM, ~350-, 75... Others
T3620 Solcitinibnew Solcitinib, also known as GSK2586184 or GLPG0778, is a Janus kinase 1 (JAK1) inhibito... Immunology
T3398 Icaritinnew Icaritin has hormone regulation activity and cardiovascular function improvement acti... Cancer
T6124 Mubritinib (TAK 165)new Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM; no activi... Cancer
T6104 Cerdulatinib hydrochloride Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor... Cancer
T6020 Pacritinib (SB1518) Pacritinib (SB1518) is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and ... Cancer
T3080 Pyridone 6 Pyridone 6(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK... Cancer
T3076 GLPG0634 analogue GLPG0634 analogue is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, an... Cancer
T3072 XL019 XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, exhibiting >50-fo... Cancer
T3069 AZD1480 AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free... Cancer
T3068 AT9283 AT9283 is a potent JAK2/3 inhibitor with IC50 of 1.2 nM/1.1 nM in cell-free assays; a... Cancer
T3065 TG101209 TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET... Cancer
T3043 Ruxolitinib phosphate Ruxolitinib phosphate(INCB018424 phosphate) is the first potent, selective, JAK1/2 in... Cancer
T3042 NSC 42834 NSC 42834(JAK2 Inhibitor V, Z3), a novel specific inhibitor of Jak2, inhibits Jak2-V6... Cancer
T2853 Curcumol Curcumol is a pure monomer isolated from Rhizoma Curcumaeis with antitumor activities... Cancer
T2709 TAK901 TAK-901 is a novel inhibitor of Aurora A/B with IC50 of 21 nM/15 nM. It is not a pote... Cancer
T2653 SB1317 SB1317/TG02 is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 ... Cancer
T2638 Gandotinib (LY2784544) LY2784544(gandotinib) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2... Cancer
T2636 Decernotinib(VX-509) Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhi... Cancer
T2600 AG-490 AG-490 (Tyrphostin AG 490) is an inhibitor of EGFR with IC50 of 0.1 μM, 135-fold more... Other
T2487 Cerdulatinib Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor. Cancer
T2485 Baricitinib Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 ... Cancer
T2460 ZM 39923 hydrochloride ZM 39923 hydrochloride is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activi... Other
1