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IGF-1R
Cat.No. Product Name Information Area
T4324 PQ401 hydrochloride (196868-63-0(free base)) PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM. Cancer
T6943 Picropodophyllin (PPP) Picropodophyllin (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin ... Others
T2693 AG1024 AG-1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM),and is less pot... Other
T6419 BMS-536924 BMS-536924 is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modes... Cancer
T6080 NVP-AEW541 NVP-AEW541, a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits... Cancer
T2107 NVP-ADW742 NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against ... Cancer
T6017 OSI-906 (Linsitinib) OSI-906 (Linsitinib) is an orally bioavailable small molecule inhibitor of the insuli... Cancer
T6003 GSK1904529A GSK1904529A is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) . Cancer
T3079 GSK1838705A GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (I... Cancer
T2491 AZ5104 AZ5104 is a potent EGFR inhibitor. Cancer
T2349 BMS-754807 Dual IGF-1R/InsR Inhibitor BMS-754807 is an oral small molecule inhibitor of insulin-... Cancer
T2085 PQ401 PQ401 suppresses autophosphorylation of IGF-1R domain(IC50<1 μM). Cancer
T1791 LDK378(Ceritinib) Ceritinib is a Kinase Inhibitor. The mechanism of action of Ceritinib is as a Tyrosin... Cancer
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