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Home > Gamma-secretase
Gamma-secretase
Cat.No. Product Name Information Area
T6935 PF-03084014 (PF-3084014) PF-03084014 (PF-3084014) is a selective gamma-secretase inhibitor with IC50 of 6.2 nM... Others
T6870 L-685,458 L-685,458 is a specific and potent inhibitor of A beta PP gamma-secretase activity wi... Others
T6861 IMR-1 IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation w... Others
T6249 Avagacestat (BMS-708163) Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhi... Cancer
T6202 DAPT (GSI-IX) DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC5... Cancer
T6135 YO-01027 (Dibenzazepine) YO-01027 (Dibenzazepine) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM an... Others
T6125 Semagacestat (LY450139) Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of... Cancer
T6063 LY411575 LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/c... Others
T3075 FLI-06 FLI-06 is a novel inhibitor of Notch signaling with EC50 of 2.3 μM. Cancer
T2639 LY2811376 LY2811376 is the first orally available non-peptidic β-secretase(BACE1) inhibitor wit... Nervous system
T2625 MK-0752 MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production w... Nervous system
T2262 CHF-5074

CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an...

Other
T6274 RO4929097 RO4929097 is a γ secretase inhibitor with IC50 of 4 nM, inhibiting cellular processin... Cancer
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