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CFTR
Cat.No. Product Name Information Area
T7083 GLPG1837 GLPG1837 is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del ... Cystic fibrosis
T3135 KM11060 KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508d... Others
T2595 VX-809 VX-809 (Lumacaftor) acts to correct CFTR mutations common in cystic fibrosis by incre... Cancer
T2588 Ivacaftor (VX-770) Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F... Cancer
T2451 GlyH-101 GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of ... Other
T2355 CFTR(inh)-172 CFTRinh-172 is a voltage-independent, selective CFTR inhibitor. Other
T2263 VX661 VX-661 is a small molecule that can be used as a corrector of the cystic fibrosis tra... Cancer
T1874 PPQ-102 PPQ-102, an effective CFTR inhibitor, can completely inhibit CFTR chloride current (I... Other
T1805 PTC124 Ataluren is a novel, orally administered drug that targets nonsense mutations. Atalur... Other
T1394 Ibuprofen Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID... Nervous system
T6307 Lubiprostone Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idio... Cardiovascular System
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