||GLPG1837 is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del ...
||KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508d...
||VX-809 (Lumacaftor) acts to correct CFTR mutations common in cystic fibrosis by incre...
||Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F...
||GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of ...
||CFTRinh-172 is a voltage-independent, selective CFTR inhibitor.
||VX-661 is a small molecule that can be used as a corrector of the cystic fibrosis tra...
||PPQ-102, an effective CFTR inhibitor, can completely inhibit CFTR chloride current (I...
||Ataluren is a novel, orally administered drug that targets nonsense mutations. Atalur...
||Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID...
||Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idio...