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ALK
Cat.No. Product Name Information Area
T4071 TPX-0005 TPX-0005 is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM an... Cancer
T4015 HG-14-10-04 HG-14-10-04 is a potent and specific ALK inhibitor. Others
T3550 Ensartinibnew Ensartinib (X-396) is an orally available small molecule inhibitor of the receptor ty... Cancer
T3621 Brigatinibnew Brigatinib is a highly potent and selective ALK inhibitor. Cancer
T3041 ALK inhibitor 2 ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase. Cancer
T3079 GSK1838705A GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (I... Cancer
T3059 AP26113 Brigatinib is a excellently effective and specific ALK inhibitor( IC50 =0.6 nM). Cancer
T3031 A 83-01 A 83-01 is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin... Immunology
T2809 Fangchinoline Fangchinoline is extracted from Stephania tetrandra S. Moore. Cardiovascular System
T2655 CEP-37440 CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(AL... Immunology
T2641 KRCA-0008 KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays d... Immunology
T2491 AZ5104 AZ5104 is a potent EGFR inhibitor. Cancer
T2465 PF-562271 PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) a... Other
T2462 SB-505124 SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5. Immunology
T2449 D4476 D4476 is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( ... Metabolism system
T2314 PF 431396 PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM). Other
T2251 NVP-TAE 684 NVP-TAE 684 is a excellently effective and specific ALK inhibitor(IC50=3 nM). Cancer
T2109 SD-208 SD-208, a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity ... Immunology
T2098 A 77-01 A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like ... Immunology
T2001 PF-573228 PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK ... Other
T1996 Defactinib (VS-6063, PF-04554878) Defactinib is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhi... Other
T1967 AZD-3463 AZD3463, an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with e... Immunology
T1962 ASP 3026 ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphom... Immunology
T1950 PND-1186 PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM). Other
T1944 LDN-214117 LDN-214117 is a potent and selective ALK2 inhibitor. Immunology
T1943 ML347 ML347(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the sele... Other
T1942 DMH-1 DMH-1 is a potent and selective BMP inhibitor. Other
T1936 CH5424802 CH5424802 is an orally available inhibitor of the receptor tyrosine kinase anaplastic... Other
T1935 LDN193189 LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcripti... Other
T1918 NVP-TAE 226 NVP-TAE226 is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC... Other
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