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Mk-6186 HCl

Name: Mk-6186 HCl
Brand: TargetMol
SKU: T68103L
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T68103L

Alias Mk-6186 HCl(1034474-19-5 Free base)

MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.

Mk-6186 HCl

🥰Excellent

Purity: 98.19%

Catalog No. T68103LAlias Mk-6186 HCl(1034474-19-5 Free base)

MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.

Pack Size	Price	Availability
1 mg	$82	In Stock
5 mg	$195	In Stock
10 mg	$285	In Stock
25 mg	$449	In Stock
50 mg	$659	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.19%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.
Synonyms	Mk-6186 HCl(1034474-19-5 Free base)

Chemical Properties

Molecular Weight	471.73
Formula	C₂₁H₁₃Cl₃N₆O
Smiles	N#CC1=CC(Cl)=CC(OC2=C(C=CC3=C2C=NN3CC4=NNC5=C4C=CC=N5)Cl)=C1.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (116.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1199 mL	10.5993 mL	21.1986 mL	105.9928 mL
5 mM	0.4240 mL	2.1199 mL	4.2397 mL	21.1986 mL
10 mM	0.2120 mL	1.0599 mL	2.1199 mL	10.5993 mL
20 mM	0.1060 mL	0.5300 mL	1.0599 mL	5.2996 mL
50 mM	0.0424 mL	0.2120 mL	0.4240 mL	2.1199 mL
100 mM	0.0212 mL	0.1060 mL	0.2120 mL	1.0599 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc