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APOL1-IN-1

🥰Excellent
Catalog No. T40109Cas No. 2446817-72-5
Alias APOL1-IN-1

APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into these diseases.

APOL1-IN-1

APOL1-IN-1

🥰Excellent
Purity: 99.76%
Catalog No. T40109Alias APOL1-IN-1Cas No. 2446817-72-5
APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into these diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$95-In Stock
5 mg$247In StockIn Stock
10 mg$397-In Stock
25 mg$817-In Stock
50 mg$1,290-In Stock
1 mL x 10 mM (in DMSO)$198-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.76%
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Product Introduction

Bioactivity
Description
APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into these diseases.
SynonymsAPOL1-IN-1
Chemical Properties
Molecular Weight381.4
FormulaC21H20FN3O3
Cas No.2446817-72-5
SmilesO[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2ccccc12)-c1ccc(F)cc1
Relative Density.1.40 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (262.19 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6219 mL13.1096 mL26.2192 mL131.0960 mL
5 mM0.5244 mL2.6219 mL5.2438 mL26.2192 mL
10 mM0.2622 mL1.3110 mL2.6219 mL13.1096 mL
20 mM0.1311 mL0.6555 mL1.3110 mL6.5548 mL
50 mM0.0524 mL0.2622 mL0.5244 mL2.6219 mL
100 mM0.0262 mL0.1311 mL0.2622 mL1.3110 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

apolipoprotein L1APOL-1-IN-1APOL1IN1APOL1 IN 1
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