Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation in states of shock and can be used in studies about organophosphate poisoning.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 313.00 | |
10 mg | In stock | $ 468.00 | |
25 mg | In stock | $ 753.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,390.00 | |
500 mg | In stock | $ 2,790.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 278.00 |
Description | Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation in states of shock and can be used in studies about organophosphate poisoning. |
In vitro | In RAW264.7 cells, Anisodamine (100 μg/mL) blocks muscarinic receptors thus allowing more endogenous ACh binding to the α-7nAChR and attenuating α-bungarotoxin binding[3]. |
In vivo | Intraperitoneal administration of Anisodamine (50 mg/kg) significantly reduces mortality of LPS-induced shock mice(20%)[3]. |
Synonyms | 6-Hydroxyhyoscyamine, 6-beta-Hydroxyhyoscyamine |
Molecular Weight | 305.37 |
Formula | C17H23NO4 |
CAS No. | 55869-99-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (294.7 mM)
H2O: 18.0 mg/mL (58.9 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Anisodamine 55869-99-3 Neuroscience AChR 6-b-Hydroxyhyoscyamine 6-Hydroxyhyoscyamine 6-beta-Hydroxyhyoscyamine 6-β-Hydroxyhyoscyamine inhibitor inhibit