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7-Methoxyflavone

Catalog No. T7907 CAS 22395-22-8

7-Methoxyflavone isolated from Zornia brasiliensis with antinociceptive effects.

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7-Methoxyflavone, CAS 22395-22-8

Pack Size	Availability	Price/USD	Quantity
100 mg	In stock	$ 66.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.51%

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Description

7-Methoxyflavone isolated from Zornia brasiliensis with antinociceptive effects.

In vivo

The antinociceptive effect of 7-methoxyflavone (7MF) in mice using the following tests: acetic acid-induced writhing, glutamate- and formalin-induced nociception and hotplate. 7MF (30, 50, 100 and 300 μmol/kg, i.p.) reduced the number of writhes, with ID?? = 82.5 ± 11.7 μmol/kg and E max = 58.4%. 7MF treatment (100 μmol/kg, i.p.) inhibited paw-licking time in the neurogenic phase of the formalin pain response (65.6%) and did not decrease the nociceptive response in the inflammatory phase. In addition, in glutamate-induced nociception, 7MF inhibited 26% of the nociceptive answer. On the other hand, 7MF did not increase the latency time of the animals in the hotplate test. These results suggest that 7MF has peripheral antinociceptive activity

Molecular Weight	252.26
Formula	C16H12O3
CAS No.	22395-22-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (99.1 mM)

References and Literature

1. Antinociceptive effect of 7-methoxyflavone isolated from Zornia brasiliensis[J]. Natural Product Letters, 2013, 27(18):1695-1699.

Related compound libraries

This product is contained In the following compound libraries：

RO5 Drug-like Natural Product Library Natural Product Library Flavonoid Natural Product Library Natural Product Library for HTS Bioactive Compounds Library Max Selected Plant-Sourced Compound Library Bioactive Compound Library NO PAINS Compound Library

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Keywords

7-Methoxyflavone 22395-22-8 Others 7Methoxyflavone Inhibitor peripheral antinociceptive 7 Methoxyflavone inflammatory inhibit paw-licking time inhibitor

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