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6-(Dimethylamino)purine

Catalog No. T7444   CAS 938-55-6
Synonyms: N,N-Dimethyladenine

6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor

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6-(Dimethylamino)purine Chemical Structure
6-(Dimethylamino)purine, CAS 938-55-6
Pack Size Availability Price/USD Quantity
250 mg In stock $ 42.00
1 mL * 10 mM (in DMSO) In stock $ 46.00
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Purity: 99.49%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor
In vitro The apoptosis was induced by 6-dimethylaminopurine(6-DMAP) in a dose- and time-dependent manner and treatment for 16 h at a concentration of 5 mM induced apparent DNA fragmentation, phosphatidylserine externalization and lowering of the mitochondrial membrane potential, which are typical markers of apoptosis[1].
Synonyms N,N-Dimethyladenine
Molecular Weight 163.18
Formula C7H9N5
CAS No. 938-55-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 32mg/mL(196.1mM)

TargetMolReferences and Literature

1. Nakashima M , Cui Z G , Tabuchi Y , et al. Apoptosis induced by an alkylated purine, 6-dimethylaminopurine, and changes in gene expression in human lymphoma U937 cells[J]. Anticancer research, 2008, 28(2A):609-620. 2. Neant I , Guerrier P . 6-Dimethylaminopurine blocks starfish oocyte maturation by inhibiting a relevant protein kinase activity[J]. Experimental Cell Research, 1988, 176(1):0-79.

Related compound libraries

This product is contained In the following compound libraries:
Natural Product Library for HTS Apoptosis Compound Library Metabolism Compound Library Nucleotide Compound Library Kinase Inhibitor Library Anti-Cancer Compound Library Bioactive Compound Library NO PAINS Compound Library Bioactive Compounds Library Max Inhibitor Library

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Keywords

6-(Dimethylamino)purine 938-55-6 Cell Cycle/Checkpoint Metabolism CDK Serine/threonin kinase Inhibitor N,N-Dimethyladenine Cyclin dependent kinase 6-Dimethylaminopurine inhibit 6(Dimethylamino)purine 6 (Dimethylamino)purine inhibitor

 

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