Powder: -20°C for 3 years | In solvent: -80°C for 1 year
3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling proteins related with cell proliferation and cell death.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 84.00 | |
5 mg | In stock | $ 196.00 | |
10 mg | In stock | $ 295.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 220.00 |
Description | 3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling proteins related with cell proliferation and cell death. |
In vitro | 3'-Demethylnobiletin significantly suppressed CD36 expression. The inhibitory effects of 3'-Demethylnobiletin toward TPA-induced SR mRNA expression are partly associated with the suppression of AP-1 and NF-κB transcriptional activities[1]. |
Source |
Molecular Weight | 388.37 |
Formula | C20H20O8 |
CAS No. | 112448-39-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (206 mM)
You can also refer to dose conversion for different animals. More
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3'-Demethylnobiletin 112448-39-2 Cell Cycle/Checkpoint Cytoskeletal Signaling DNA Damage/DNA Repair Metabolism NF-Κb Integrin Lipoxygenase NF-κB LDL DNA/RNA Synthesis inhibit 3' Demethylnobiletin Inhibitor 3'Demethylnobiletin inhibitor