Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 43.00 | |
25 mg | In stock | $ 64.00 | |
50 mg | In stock | $ 79.00 | |
100 mg | In stock | $ 133.00 | |
500 mg | In stock | $ 336.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 30.00 |
Description | 2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively) |
Targets&IC50 | A2A:80nM(Ki) , A1:300nM(Ki) , A3:1,900 nM(Ki) |
In vivo | 2-Chloroadenosine(CADO) has been used to activate adenosine receptors in the thalamus, generating anticonvulsive activity in a rat model of generalized seizures.?It has also been used to induce bronchoconstrictor effects in a guinea pig model of asthma and to study cardiovascular responses in normotensive and hypertensive rats |
Molecular Weight | 301.69 |
Formula | C10H12ClN5O4 |
CAS No. | 146-77-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (149.16 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
2-Chloroadenosine 146-77-0 GPCR/G Protein Neuroscience Adenosine Receptor permeant Inhibitor influx,nitrobenzylthioinosine inhibit cell human 2 Chloroadenosine transported analogue loss 2Chloroadenosine ischaemic erythrocytes,uridine inhibitor